Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Natural DNP-binding immunoglobulins and antibody multispecificity.

Literature DB >> 6504050

Natural DNP-binding immunoglobulins and antibody multispecificity.

Abstract

Anti-DNP activity was found in normal human immunoglobulins with average affinities (10(4)-10(6) l/mole) and frequencies (15-2%) that correlate well with those expected from multispecific binding sites.

Entities: Chemical Species

Mesh：

Substances：

Year: 1984 PMID： 6504050 DOI： 10.1016/0161-5890(84)90143-3

Source DB: PubMed Journal: Mol Immunol ISSN： 0161-5890 Impact factor: 4.407

Keyword Cloud
Cited

10 in total

1. A remote arene-binding site on prostate specific membrane antigen revealed by antibody-recruiting small molecules.

Authors: Andrew X Zhang; Ryan P Murelli; Cyril Barinka; Julien Michel; Alexandra Cocleaza; William L Jorgensen; Jacek Lubkowski; David A Spiegel
Journal: J Am Chem Soc Date: 2010-09-15 Impact factor: 15.419

Review 2. Development of antibody surrogates for the treatment of cancers and autoimmune disease.

Authors: Thomas Kodadek
Journal: Curr Opin Chem Biol Date: 2010-07-31 Impact factor: 8.822

3. Exploring binding and effector functions of natural human antibodies using synthetic immunomodulators.

Authors: Charles E Jakobsche; Christopher G Parker; Ran N Tao; Mariya D Kolesnikova; Eugene F Douglass; David A Spiegel
Journal: ACS Chem Biol Date: 2013-09-20 Impact factor: 5.100

4. Rhamnose glycoconjugates for the recruitment of endogenous anti-carbohydrate antibodies to tumor cells.

Authors: Rachael T C Sheridan; Jonathan Hudon; Jacquelyn A Hank; Paul M Sondel; Laura L Kiessling
Journal: Chembiochem Date: 2014-06-06 Impact factor: 3.164

5. Illuminating HIV gp120-Ligand Recognition through Computationally-Driven Optimization of Antibody-Recruiting Molecules.

Authors: Christopher G Parker; Markus K Dahlgren; Ran N Tao; Don T Li; Eugene F Douglass; Takuji Shoda; Navneet Jawanda; Krasimir A Spasov; Sangil Lee; Nannan Zhou; Robert A Domaoal; Richard E Sutton; Karen S Anderson; William L Jorgensen; Mark Krystal; David A Spiegel
Journal: Chem Sci Date: 2014-06-01 Impact factor: 9.825

Natural DNP-binding immunoglobulins and antibody multispecificity.

1. A remote arene-binding site on prostate specific membrane antigen revealed by antibody-recruiting small molecules.

Review 2. Development of antibody surrogates for the treatment of cancers and autoimmune disease.

3. Exploring binding and effector functions of natural human antibodies using synthetic immunomodulators.

4. Rhamnose glycoconjugates for the recruitment of endogenous anti-carbohydrate antibodies to tumor cells.

5. Illuminating HIV gp120-Ligand Recognition through Computationally-Driven Optimization of Antibody-Recruiting Molecules.

6. Reprogramming urokinase into an antibody-recruiting anticancer agent.

Review 7. Antibody-recruiting molecules: an emerging paradigm for engaging immune function in treating human disease.

8. An antibody-recruiting small molecule that targets HIV gp120.

9. Chemical control over immune recognition: a class of antibody-recruiting small molecules that target prostate cancer.

10. Interaction of clinical-stage antibodies with heme predicts their physiochemical and binding qualities.