| Literature DB >> 6503611 |
E F Bandle, G Wendt, U B Ranalder, K H Trautmann.
Abstract
2-Pyrrolidinone and succinimide were identified in blood plasma of man, rat, and mouse. Dog plasma contained only traces of 2-pyrrolidinone not exceeding significantly the detection limit of our GCMS-method. Succinimide but not 2-pyrrolidinone could also be found in the brains of rat and mouse. Evidence is presented for a metabolic pathway leading from 2-pyrrolidinone to succinimide, with 5-hydroxy-2-pyrrolidinone as an intermediate.Entities:
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Year: 1984 PMID： 6503611 DOI： 10.1016/0024-3205(84)90461-2
Source DB: PubMed Journal: Life Sci ISSN： 0024-3205 Impact factor: 5.037