| Literature DB >> 6502503 |
S Wahlgren, A L Lindstrom, S E Friberg.
Abstract
A lecithin-water lyotropic liquid crystal was used as an ointment vehicle for a hydrocortisone formulation. The hydrocortisone was soluble in the liquid crystalline phase up to 5% by weight. The diffusion coefficient determined for the hydrocortisone in the liquid crystalline phase was 5.5 X 10(-9) cm X s-1, which is four magnitudes higher than the corresponding value for skin.Entities:
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Year: 1984 PMID： 6502503 DOI： 10.1002/jps.2600731042
Source DB: PubMed Journal: J Pharm Sci ISSN： 0022-3549 Impact factor: 3.534