| Literature DB >> 6502480 |
J C Liu, J R Feldkamp, J L White, S L Hem.
Abstract
Phosphate is specifically adsorbed by aluminum hydroxycarbonate by anion ligand exchange. IR analysis indicated that phosphate exchanged with specifically adsorbed carbonate. Adsorption is favored by low pH and is inversely related to particle size. Adsorption of phosphate decreases the rate of acid neutralization of aluminum hydroxycarbonate. The results are applied to the treatment of hyperphosphatemia and hypophosphatemia.Entities:
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Year: 1984 PMID: 6502480 DOI: 10.1002/jps.2600731007
Source DB: PubMed Journal: J Pharm Sci ISSN: 0022-3549 Impact factor: 3.534