| Literature DB >> 65023 |
E Goulmy, A Termijtelen, B A Bradley, J J van Rood.
Abstract
The aim of our study was to define target determinants other than those coded for by the classical HLA-A, -B, -C or -D loci which were responsible for killing in CML. In one of the families studied, strong evidence was found for the existence of a determinant coded for within the HLA region. CML was restricted to targets carrying the classical HLA-Bw35 and Cw4 determinants but the targets were neither HLA-Bw35 nor Cw4 themselves. We therefore concluded that this new HLA determinant was either the product of a new locus closely associated with HLA-B or that it was a product of the classical HLA-B locus which has not been recognized by serology.Entities:
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Year: 1976 PMID： 65023 DOI： 10.1111/j.1399-0039.1976.tb00583.x
Source DB: PubMed Journal: Tissue Antigens ISSN： 0001-2815