Literature DB >> 6501316

Structures of the neutral oligosaccharides isolated from A-active human gastric mucin.

A Slomiany, E Zdebska, B L Slomiany.   

Abstract

Alkaline borohydride reductive cleavage of the mucin, purified from gastric aspirates of the secretors with blood group A, resulted in a heterogeneous population of neutral (79.7%) and acidic (20.3%) oligosaccharide alditols. Nine oligosaccharides (I-IX), ranging from 6 to 15 sugar units, have been purified from the neutral oligosaccharide fraction. Based on the results of immunological assays, sugar composition, degradation with specific exoglycosidases, and methylation analyses, we propose the following structures for these oligosaccharides: (sequence in text)

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Year:  1984        PMID: 6501316

Source DB:  PubMed          Journal:  J Biol Chem        ISSN: 0021-9258            Impact factor:   5.157


  12 in total

1.  Alterations in gastric mucin synthesis by Helicobacter pylori.

Authors:  James C Byrd; Robert S Bresalier
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2.  The oligomeric structure of rat and human gastric mucins.

Authors:  J Dekker; P H Aelmans; G J Strous
Journal:  Biochem J       Date:  1991-07-15       Impact factor: 3.857

Review 3.  Mucin glycoproteins in neoplasia.

Authors:  Y S Kim; J Gum; I Brockhausen
Journal:  Glycoconj J       Date:  1996-10       Impact factor: 2.916

4.  Sialic acid glycoproteins inhibit in vitro and in vivo replication of rotaviruses.

Authors:  R H Yolken; R Willoughby; S B Wee; R Miskuff; S Vonderfecht
Journal:  J Clin Invest       Date:  1987-01       Impact factor: 14.808

5.  Sd(a)-antigen-like structures carried on core 3 are prominent features of glycans from the mucin of normal human descending colon.

Authors:  C Capon; E Maes; J C Michalski; H Leffler; Y S Kim
Journal:  Biochem J       Date:  2001-09-15       Impact factor: 3.857

6.  Fermentation of mucin by bifidobacteria from rectal samples of humans and rectal and intestinal samples of animals.

Authors:  J Killer; M Marounek
Journal:  Folia Microbiol (Praha)       Date:  2011-04-06       Impact factor: 2.099

7.  Carbohydrate heterogeneity of fibronectins. Synovial fluid fibronectin resembles the form secreted by cultured synoviocytes but differs from the plasma form.

Authors:  S Carsons; B B Lavietes; A Slomiany; H S Diamond; E Berkowitz
Journal:  J Clin Invest       Date:  1987-11       Impact factor: 14.808

8.  Glycoconjugate expression in normal, metaplastic, and neoplastic human upper gastrointestinal mucosa.

Authors:  C Shimamoto; W M Weinstein; C R Boland
Journal:  J Clin Invest       Date:  1987-12       Impact factor: 14.808

9.  Interaction of bile salts with gastrointestinal mucins.

Authors:  Timothy Scott Wiedmann; Wei Liang; Heather Herrington
Journal:  Lipids       Date:  2004-01       Impact factor: 1.880

10.  Mucin degradation in human colon ecosystems. Isolation and properties of fecal strains that degrade ABH blood group antigens and oligosaccharides from mucin glycoproteins.

Authors:  L C Hoskins; M Agustines; W B McKee; E T Boulding; M Kriaris; G Niedermeyer
Journal:  J Clin Invest       Date:  1985-03       Impact factor: 14.808

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