Literature DB >> 6501088

Studies on new antiplatelet agents, WS-30581 A and B.

K Umehara, K Yoshida, M Okamoto, M Iwami, H Tanaka, M Kohsaka, H Imanaka.   

Abstract

WS-30581 A and B are antiplatelet agents produced by a strain of Streptoverticillium waksmanii. The compounds were purified by solvent extraction and column chromatography, and identified as new pimprinine analogs on the basis of their physico-chemical properties. The producing organism produced pimprinine along with these compounds. Pimprinine and the two new analogs have potent inhibitory effects on platelet aggregation.

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Year:  1984        PMID: 6501088     DOI: 10.7164/antibiotics.37.1153

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  2 in total

1.  Antiviral effects against EV71 of pimprinine and its derivatives isolated from Streptomyces sp.

Authors:  Yanhong Wei; Wei Fang; Zhongyi Wan; Kaimei Wang; Qingyu Yang; Xiaofeng Cai; Liqiao Shi; Ziwen Yang
Journal:  Virol J       Date:  2014-11-20       Impact factor: 4.099

2.  Identification and isolation of insecticidal oxazoles from Pseudomonas spp.

Authors:  Florian Grundmann; Veronika Dill; Andrea Dowling; Aunchalee Thanwisai; Edna Bode; Narisara Chantratita; Richard Ffrench-Constant; Helge B Bode
Journal:  Beilstein J Org Chem       Date:  2012-05-18       Impact factor: 2.883

  2 in total

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