Literature DB >> 6500846

Pantethine and pantothenate effect on the CoA content of rat liver.

D Branca, G Scutari, N Siliprandi.   

Abstract

The role of pantethine as a precursor of CoA in rat liver has been examined. It has been demonstrated that pantethine induces a significant increase in the total CoA content both in perfused liver and in liver homogenate, while it fails to affect the mitochondrial CoA content when added to isolated mitochondria. Pantethine is more efficient than pantothenate in inducing the synthesis of CoA in rat liver, even in the presence of added cysteine. The possible metabolic implications are discussed.

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Year:  1984        PMID： 6500846

Source DB:  PubMed          Journal:  Int J Vitam Nutr Res        ISSN： 0300-9831            Impact factor:   1.784


  6 in total

1.  Metabolism of pantethine in cystinosis.

Authors:  C T Wittwer; W A Gahl; J D Butler; M Zatz; J G Thoene
Journal:  J Clin Invest       Date:  1985-10       Impact factor: 14.808

2.  Protection against cerebral malaria by the low-molecular-weight thiol pantethine.

Authors:  Marie-France Penet; Mhamad Abou-Hamdan; Nicolas Coltel; Emilie Cornille; Georges E Grau; Max de Reggi; Bouchra Gharib
Journal:  Proc Natl Acad Sci U S A       Date:  2008-01-14       Impact factor: 11.205

3.  Pantethine, a derivative of vitamin B5, favorably alters total, LDL and non-HDL cholesterol in low to moderate cardiovascular risk subjects eligible for statin therapy: a triple-blinded placebo and diet-controlled investigation.

Authors:  Malkanthi Evans; John A Rumberger; Isao Azumano; Joseph J Napolitano; Danielle Citrolo; Toshikazu Kamiya
Journal:  Vasc Health Risk Manag       Date:  2014-02-27

4.  Antioxidants selenomethionine and D-pantethine decrease the negative side effects of doxorubicin in NL/Ly lymphoma-bearing mice.

Authors:  Rostyslav R Panchuk; Nadia R Skorokhyd; Yuliya S Kozak; Liliya V Lehka; Vira V Chumak; Sofya N Omelyanchik; Valery A Gurinovich; Andrey G Moiseenok; Rostyslav S Stoika
Journal:  Croat Med J       Date:  2016-04-23       Impact factor: 1.351

5.  Effect of Pantethine on Ovarian Tumor Progression and Choline Metabolism.

Authors:  Marie-France Penet; Balaji Krishnamachary; Flonne Wildes; Yelena Mironchik; Delia Mezzanzanica; Franca Podo; Max de Reggi; Bouchra Gharib; Zaver M Bhujwalla
Journal:  Front Oncol       Date:  2016-11-16       Impact factor: 6.244

Review 6.  Natural Molecules and Neuroprotection: Kynurenic Acid, Pantethine and α-Lipoic Acid.

Authors:  Fanni Tóth; Edina Katalin Cseh; László Vécsei
Journal:  Int J Mol Sci       Date:  2021-01-02       Impact factor: 5.923
  6 in total

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