| Literature DB >> 6500155 |
J J Michiels, J Stibbe, E Vellenga, H H van Vliet.
Abstract
Prophylactic treatment of two asymptomatic antithrombin III (AT III) -deficient women with oral anticoagulants and heparin during pregnancy and after delivery appeared to be feasible. Oral anticoagulants caused no change in plasma AT III levels in either woman. A high dose of heparin intravenously in one of them caused a strong reduction in the AT III level which was corrected by infusion of AT III concentrate during delivery. A low dose of heparin subcutaneously in the other caused no significant change in plasma AT III levels. There is probably no need for AT III substitution during an uncomplicated pregnancy.Entities:
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Year: 1984 PMID： 6500155 DOI： 10.1016/0028-2243(84)90013-3
Source DB: PubMed Journal: Eur J Obstet Gynecol Reprod Biol ISSN： 0301-2115 Impact factor: 2.435