| Literature DB >> 6498854 |
A K Kao, F M Muggia, N Dubin, W A Lerner, R Stark, J C Wernz, J L Speyer, R H Blum.
Abstract
Twenty-nine patients (two with small bowel cancer and 27 with colorectal cancer) were treated with a sequential 5-FU-hydroxyurea combination following the suggestion of schedule-dependent synergism in experimental systems. No enhanced toxicity was observed, but the response rate was only 4%. Seven additional patients manifested greater than or equal to 50% declines in CEA, but caution must be used in interpreting such changes as antitumor activity.Entities:
Mesh：
Substances：
Year: 1984 PMID： 6498854
Source DB: PubMed Journal: Cancer Treat Rep ISSN： 0361-5960