Literature DB >> 6498580

Lack of tolerance to cyclopropane and cross-tolerance to halothane in rats.

E S Munson.   

Abstract

Cyclopropane requirement (MAC) in rats was determined before, during, and after repeated exposure to anaesthetic concentrations of cyclopropane and halothane for one hour every day for 20 and 30 days, respectively. MAC values during and after exposure ranged from 93 to 103 per cent (mean = 99 per cent) of control values, which indicates a lack of significant tolerance to cyclopropane or a cross-tolerance between cyclopropane and halothane.

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Year:  1984        PMID： 6498580     DOI： 10.1007/bf03008760

Source DB:  PubMed          Journal:  Can Anaesth Soc J        ISSN： 0008-2856


  8 in total

1.  Effects of acute and chronic ethanol administration on isoflurane requirement in mice.

Authors:  R E Johnstone; R A Kulp; T C Smith
Journal:  Anesth Analg       Date:  1975 May-Jun       Impact factor: 5.108

2.  Convulsions in mice after anesthesia.

Authors:  R A Smith; P M Winter; M Smith; E I Eger
Journal:  Anesthesiology       Date:  1979-06       Impact factor: 7.892

3.  Rapidly developing tolerance to acute exposures to anesthetic agents.

Authors:  R A Smith; P M Winter; M Smith; E I Eger
Journal:  Anesthesiology       Date:  1979-06       Impact factor: 7.892

4.  Circadian variations in anesthetic requirement and toxicity in rats.

Authors:  E S Munson; R W Martucci; R E Smith
Journal:  Anesthesiology       Date:  1970-06       Impact factor: 7.892

5.  Minimum alveolar anesthetic concentration: a standard of anesthetic potency.

Authors:  E I Eger; L J Saidman; B Brandstater
Journal:  Anesthesiology       Date:  1965 Nov-Dec       Impact factor: 7.892

6.  Tolerance to and dependence on inhalational anesthetics.

Authors:  R A Smith; P M Winter; M Smith; E I Eger
Journal:  Anesthesiology       Date:  1979-06       Impact factor: 7.892

7.  The effects of acute hypothyroidism and hyperthyroidism on cyclopropane requirement (MAC) in rats.

Authors:  E S Munson; J C Hoffman; C A DiFazio
Journal:  Anesthesiology       Date:  1968 Nov-Dec       Impact factor: 7.892

8.  Murine auto- and cross-tolerance to volatile anaesthetics.

Authors:  J Chalon; C K Tang; C Roberts; L Walpert; C Hoffman; S Ramanathan; H Turndorf
Journal:  Can Anaesth Soc J       Date:  1983-05
  8 in total

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