Literature DB >> 6498199

Preferential stimulation of rabbit alpha globin mRNA translation by a cap-binding protein complex.

G Sarkar, I Edery, R Gallo, N Sonenberg.   

Abstract

A cap-binding protein complex (Edery et al. (1983) J. Biol. Chem. 258, 11398-11403) is shown here to stimulate preferentially the translation of endogenous alpha versus beta globin mRNA in a rabbit reticulocyte lysate. Several initiation factors (eIF-2, eIF-3, eIF-4A, eIF-4B, eIF-4C, eIF-4E and eIF-5) and elongation factor 1 were found to have no such discriminatory effect. These results are in contrast to several previous reports and demonstrate that the only factor capable of relieving translational competition between alpha and beta globin mRNAs is the cap-binding protein complex.

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Year:  1984        PMID： 6498199     DOI： 10.1016/0167-4781(84)90003-4

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  14 in total

1.  In vitro transcription and translational efficiency of chimeric SP6 messenger RNAs devoid of 5' vector nucleotides.

Authors:  S A Jobling; C M Cuthbert; S G Rogers; R T Fraley; L Gehrke
Journal:  Nucleic Acids Res       Date:  1988-05-25       Impact factor: 16.971

2.  Contribution of polyadenylate sequences to the translational efficiency of globin messenger RNAs.

Authors:  A Parets Soler; D Gozalbo; J Zueco; R Sentandreu
Journal:  Biochem J       Date:  1987-09-15       Impact factor: 3.857

3.  Overexpression of initiation factor eIF-4E does not relieve the translational repression of ribosomal protein mRNAs in quiescent cells.

Authors:  S Shama; D Avni; R M Frederickson; N Sonenberg; O Meyuhas
Journal:  Gene Expr       Date:  1995

4.  Phosphorylation of eukaryotic translation initiation factor 4E is increased in Src-transformed cell lines.

Authors:  R M Frederickson; K S Montine; N Sonenberg
Journal:  Mol Cell Biol       Date:  1991-05       Impact factor: 4.272

Review 5.  Targeting the eIF4F translation initiation complex: a critical nexus for cancer development.

Authors:  Jerry Pelletier; Jeremy Graff; Davide Ruggero; Nahum Sonenberg
Journal:  Cancer Res       Date:  2015-01-15       Impact factor: 12.701

6.  Cap-binding protein (eukaryotic initiation factor 4E) and 4E-inactivating protein BP-1 independently regulate cap-dependent translation.

Authors:  D Feigenblum; R J Schneider
Journal:  Mol Cell Biol       Date:  1996-10       Impact factor: 4.272

7.  A fraction of the mRNA 5' cap-binding protein, eukaryotic initiation factor 4E, localizes to the nucleus.

Authors:  F Lejbkowicz; C Goyer; A Darveau; S Neron; R Lemieux; N Sonenberg
Journal:  Proc Natl Acad Sci U S A       Date:  1992-10-15       Impact factor: 11.205

8.  TIF4631 and TIF4632: two yeast genes encoding the high-molecular-weight subunits of the cap-binding protein complex (eukaryotic initiation factor 4F) contain an RNA recognition motif-like sequence and carry out an essential function.

Authors:  C Goyer; M Altmann; H S Lee; A Blanc; M Deshmukh; J L Woolford; H Trachsel; N Sonenberg
Journal:  Mol Cell Biol       Date:  1993-08       Impact factor: 4.272

9.  Photochemical cross-linking of cap binding proteins to eucaryotic mRNAs: effect of mRNA 5' secondary structure.

Authors:  J Pelletier; N Sonenberg
Journal:  Mol Cell Biol       Date:  1985-11       Impact factor: 4.272

10.  A late adenovirus factor induces eIF-4E dephosphorylation and inhibition of cell protein synthesis.

Authors:  Y Zhang; D Feigenblum; R J Schneider
Journal:  J Virol       Date:  1994-11       Impact factor: 5.103
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