Literature DB >> 6497531

Cerebellar ataxia due to procainamide toxicity.

A B Schwartz, S C Klausner, S Yee, M Turchyn.   

Abstract

It has become appreciated that drug levels of procainamide hydrochloride needed to suppress inducible ventricular tachycardia by programmed ventricular stimulation exceed the previously published therapeutic range. Cerebellar ataxia developed acutely in a patient receiving high-dose procainamide. This was associated with a marked increase in the serum drug level. Resolution occurred within three days after drug therapy was discontinued.

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Year:  1984        PMID: 6497531

Source DB:  PubMed          Journal:  Arch Intern Med        ISSN: 0003-9926


  3 in total

Review 1.  Adverse effects of class I antiarrhythmic drugs.

Authors:  J Caron; C Libersa
Journal:  Drug Saf       Date:  1997-07       Impact factor: 5.606

2.  Myopathy after short term administration of procainamide.

Authors:  C A Lewis; N Boheimer; P Rose; G Jackson
Journal:  Br Med J (Clin Res Ed)       Date:  1986-03-01

Review 3.  Poisoning due to class IA antiarrhythmic drugs. Quinidine, procainamide and disopyramide.

Authors:  S Y Kim; N L Benowitz
Journal:  Drug Saf       Date:  1990 Nov-Dec       Impact factor: 5.606

  3 in total

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