| Literature DB >> 649628 |
S J Gourlay, R M Rice, A F Hegyeli, C W Wade, J G Dillon, H Jaffe, R K Kulkarni.
Abstract
An in vivo method is described for screening polymeric materials for biocompatibility. The test is based on grading acute and subacute tissue reactions at 7 and 28 days, respectively, following implantation in rats. The methods is reproducible and reliable. It is designed to provide uniform test criteria for biocompatibility assessment in the early phases of the development of surgical implant materials.Entities:
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Year: 1978 PMID: 649628 DOI: 10.1002/jbm.820120207
Source DB: PubMed Journal: J Biomed Mater Res ISSN: 0021-9304