Literature DB >> 649628

Biocompatibility testing of polymers: in vivo implantation studies.

S J Gourlay, R M Rice, A F Hegyeli, C W Wade, J G Dillon, H Jaffe, R K Kulkarni.   

Abstract

An in vivo method is described for screening polymeric materials for biocompatibility. The test is based on grading acute and subacute tissue reactions at 7 and 28 days, respectively, following implantation in rats. The methods is reproducible and reliable. It is designed to provide uniform test criteria for biocompatibility assessment in the early phases of the development of surgical implant materials.

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Year:  1978        PMID: 649628     DOI: 10.1002/jbm.820120207

Source DB:  PubMed          Journal:  J Biomed Mater Res        ISSN: 0021-9304


  5 in total

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Authors:  Rajesh Singh; Shailesh Singh; James W Lillard
Journal:  J Pharm Sci       Date:  2008-07       Impact factor: 3.534

2.  The interface between ionomer cement and bone in the porcine cervical spine.

Authors:  J J Langmayr; P Seykora; R Jakober; G Klima; M Ortler
Journal:  Acta Neurochir (Wien)       Date:  1996       Impact factor: 2.216

3.  Short-term in vitro and in vivo biocompatibility of a biodegradable polyurethane foam based on 1,4-butanediisocyanate.

Authors:  B van Minnen; M B M van Leeuwen; B Stegenga; J Zuidema; C E Hissink; T G van Kooten; R R M Bos
Journal:  J Mater Sci Mater Med       Date:  2005-03       Impact factor: 3.896

4.  The use of vancomycin-loaded poly-l-lactic acid and poly-ethylene oxide microspheres for bone repair: an in vivo study.

Authors:  Débora Cristina Coraca-Huber; Eliana Aparecida de Rezende Duek; Maurício Etchebehere; Luis Alberto Magna; Eliane Maria Ingrid Amstalden
Journal:  Clinics (Sao Paulo)       Date:  2012-07       Impact factor: 2.365

5.  Are Biodegradable Osteosyntheses Still an Option for Midface Trauma? Longitudinal Evaluation of Three Different PLA-Based Materials.

Authors:  Andreas Kolk; Robert Köhnke; Christoph H Saely; Oliver Ploder
Journal:  Biomed Res Int       Date:  2015-09-27       Impact factor: 3.411

  5 in total

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