Literature DB >> 6493793

The formalin test: a tonic pain model in the primate.

Meenakshi Alreja1, Pradeep Mutalik, Usha Nayar, S K Manchanda.   

Abstract

The formalin test has been used in monkeys for assessing pain. After formalin injection in the palmar surface of the hand just proximal to the base of the fingers, the monkey's responses are rated for 1 h according to objective behavioral criteria. The present 'tonic' pain model has a fair degree of objectivity, validity, reproducibility and quantifiability. The analgesic effects of morphine and pethidine have been evaluated.

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Year:  1984        PMID： 6493793     DOI： 10.1016/0304-3959(84)90815-7

Source DB:  PubMed          Journal:  Pain        ISSN： 0304-3959            Impact factor:   6.961


  8 in total

1.  Cerebrovascular responses of the rat brain to noxious stimuli as examined by functional near-infrared whole brain imaging.

Authors:  Ji-Wei He; Fenghua Tian; Hanli Liu; Yuan Bo Peng
Journal:  J Neurophysiol       Date:  2012-02-29       Impact factor: 2.714

Review 2.  Kappa opioids and the modulation of pain.

Authors:  Bronwyn Kivell; Thomas E Prisinzano
Journal:  Psychopharmacology (Berl)       Date:  2010-04-07       Impact factor: 4.530

3.  Standardization of the rat paw formalin test for the evaluation of analgesics.

Authors:  H Wheeler-Aceto; A Cowan
Journal:  Psychopharmacology (Berl)       Date:  1991       Impact factor: 4.530

4.  Cortical NR2B NMDA subunit antagonism reduces inflammatory pain in male and female rats.

Authors:  Gabriel C Quintero; Jairo Herrera; José Bethancourt
Journal:  J Pain Res       Date:  2011-09-26       Impact factor: 3.133

5.  Antinociceptive Effects of Spinal Manipulative Therapy on Nociceptive Behavior of Adult Rats during the Formalin Test.

Authors:  Stephen M Onifer; William R Reed; Randall S Sozio; Cynthia R Long
Journal:  Evid Based Complement Alternat Med       Date:  2015-11-26       Impact factor: 2.629

6.  Stereotypical Escape Behavior in Caenorhabditis elegans Allows Quantification of Effective Heat Stimulus Level.

Authors:  Kawai Leung; Aylia Mohammadi; William S Ryu; Ilya Nemenman
Journal:  PLoS Comput Biol       Date:  2016-12-27       Impact factor: 4.475

7.  Involvement of endoplasmic reticulum stress in formalin-induced pain is attenuated by 4-phenylbutyric acid.

Authors:  Fan Zhou; Wei Zhang; Jianmei Zhou; Meirong Li; Feng Zhong; Yun Zhang; Yuezhu Liu; Yaping Wang
Journal:  J Pain Res       Date:  2017-03-20       Impact factor: 3.133

8.  The formalin test does not probe inflammatory pain but excitotoxicity in rodent skin.

Authors:  Tal Hoffmann; Florian Klemm; Tatjana I Kichko; Susanne K Sauer; Katrin Kistner; Bernhard Riedl; Patrick Raboisson; Lei Luo; Alexandru Babes; Laurence Kocher; Giancarlo Carli; Michael J M Fischer; Peter W Reeh
Journal:  Physiol Rep       Date:  2022-03
  8 in total

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