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Literature DB >> 6493613

Dopaminergic activity is reduced in diabetic rats.

Abstract

Dopamine synthesis rates in synaptosomes prepared from the striata of alloxan-diabetic rats were considerably lower than in control preparations. Striatal dopamine metabolite levels, after an initial increase, were also reduced at 3 and 6 weeks after alloxan administration. These findings suggest that dopaminergic functioning may be impaired in diabetic rats.

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Year: 1984 PMID： 6493613 DOI： 10.1016/0304-3940(84)90306-9

Source DB: PubMed Journal: Neurosci Lett ISSN： 0304-3940 Impact factor: 3.046

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Cited

16 in total

1. Common variations in 4p locus are related to male completed suicide.

Authors: Anne Must; Sulev Kõks; Eero Vasar; Gunnar Tasa; Aavo Lang; Eduard Maron; Marika Väli
Journal: Neuromolecular Med Date: 2008-12-25 Impact factor: 3.843

2. Enhanced nicotine self-administration and suppressed dopaminergic systems in a rat model of diabetes.

Authors: Laura E O'Dell; Luis A Natividad; Joseph A Pipkin; Francisco Roman; Ivan Torres; Jesus Jurado; Oscar V Torres; Theodore C Friedman; John M Tenayuca; Arbi Nazarian
Journal: Addict Biol Date: 2013-07-08 Impact factor: 4.280

Review 3. You are what you eat: influence of type and amount of food consumed on central dopamine systems and the behavioral effects of direct- and indirect-acting dopamine receptor agonists.

Authors: Michelle G Baladi; Lynette C Daws; Charles P France
Journal: Neuropharmacology Date: 2012-02-23 Impact factor: 5.250

4. Reduced insulin-receptor mediated modulation of striatal dopamine release by basal insulin as a possible contributing factor to hyperdopaminergia in schizophrenia.

Authors: Fernando Caravaggio; Margaret Hahn; Shinichiro Nakajima; Philip Gerretsen; Gary Remington; Ariel Graff-Guerrero
Journal: Med Hypotheses Date: 2015-06-24 Impact factor: 1.538

10. Regionally-specific alterations in mesotelencephalic dopamine synthesis in diabetic rats: association with precursor tyrosine.

Authors: C W Bradberry; D H Karasic; A Y Deutch; R H Roth
Journal: J Neural Transm Gen Sect Date: 1989

Dopaminergic activity is reduced in diabetic rats.

1. Common variations in 4p locus are related to male completed suicide.

2. Enhanced nicotine self-administration and suppressed dopaminergic systems in a rat model of diabetes.

Review 3. You are what you eat: influence of type and amount of food consumed on central dopamine systems and the behavioral effects of direct- and indirect-acting dopamine receptor agonists.

4. Reduced insulin-receptor mediated modulation of striatal dopamine release by basal insulin as a possible contributing factor to hyperdopaminergia in schizophrenia.

5. Behavioral effects of amphetamine in streptozotocin-treated rats.

6. Hypoglycemia induced changes in cholinergic receptor expression in the cerebellum of diabetic rats.

Review 7. Brain insulin dysregulation: implication for neurological and neuropsychiatric disorders.

8. Association of diabetes with dyskinesia in older psychosis patients.

9. Changes in the central dopaminergic systems in the streptozotocin-induced diabetic rats.

10. Regionally-specific alterations in mesotelencephalic dopamine synthesis in diabetic rats: association with precursor tyrosine.