| Literature DB >> 6491963 |
J F Brower, D Y Toler, J C Reepmeyer.
Abstract
Sodium levothyroxine was determined in bulk drugs, tablets, and injections by high-performance liquid chromatography (HPLC). Levothyroxine was separated from excipients and impurities on a 10-microns cyanoalkyl column using an acetonitrile-water-phosphoric acid mobile phase. The HPLC method is shown to be linear, accurate, and precise, and the results obtained by the HPLC and USP XX methods are compared.Entities:
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Year: 1984 PMID： 6491963 DOI： 10.1002/jps.2600730937
Source DB: PubMed Journal: J Pharm Sci ISSN： 0022-3549 Impact factor: 3.534