Literature DB >> 6491960

Distribution and elimination of polymethyl methacrylate nanoparticles after peroral administration to rats.

M Nefzger, J Kreuter, R Voges, E Liehl, R Czok.   

Abstract

Polymethyl [1-14C]methacrylate nanoparticles were administered orally to bile cannulated rats. Ten to fifteen percent of the administered radioactivity was absorbed and found in the bile and urine. Within 48 h, 94-97% of the absorbed radioactivity had been eliminated from the body. After 8 d, the highest residual radioactivity was found in the bone marrow, fatty renal tissue, stomach, liver, and lymph nodes.

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Year:  1984        PMID： 6491960     DOI： 10.1002/jps.2600730934

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN： 0022-3549            Impact factor:   3.534


  7 in total

Review 1.  The oral absorption of micro- and nanoparticulates: neither exceptional nor unusual.

Authors:  A T Florence
Journal:  Pharm Res       Date:  1997-03       Impact factor: 4.200

Review 2.  Nano-Technological Approaches for Targeting Kidney Diseases With Focus on Diabetic Nephropathy: Recent Progress, and Future Perspectives.

Authors:  Bo Lin; Ying-Yu Ma; Jun-Wei Wang
Journal:  Front Bioeng Biotechnol       Date:  2022-05-13

3.  Circulation and long-term fate of functionalized, biocompatible single-walled carbon nanotubes in mice probed by Raman spectroscopy.

Authors:  Zhuang Liu; Corrine Davis; Weibo Cai; Lina He; Xiaoyuan Chen; Hongjie Dai
Journal:  Proc Natl Acad Sci U S A       Date:  2008-01-29       Impact factor: 11.205

Review 4.  Entering the era of nanoscience: time to be so small.

Authors:  Vuk Uskoković
Journal:  J Biomed Nanotechnol       Date:  2013-09       Impact factor: 4.099

5.  The potential risks of nanomaterials: a review carried out for ECETOC.

Authors:  Paul J A Borm; David Robbins; Stephan Haubold; Thomas Kuhlbusch; Heinz Fissan; Ken Donaldson; Roel Schins; Vicki Stone; Wolfgang Kreyling; Jurgen Lademann; Jean Krutmann; David Warheit; Eva Oberdorster
Journal:  Part Fibre Toxicol       Date:  2006-08-14       Impact factor: 9.400

6.  Effect of IGF-1C domain-modified nanoparticles on renal ischemia-reperfusion injury in mice.

Authors:  Meng Xu; Mingyue Zhao; Donghui Zheng
Journal:  Ren Fail       Date:  2022-12       Impact factor: 3.222

Review 7.  Administration of Silver Nanoparticles in Diabetes Mellitus: A Systematic Review and Meta-analysis on Animal Studies.

Authors:  Farnaz Torabian; Arash Akhavan Rezayat; Mohammad Ghasemi Nour; Atefeh Ghorbanzadeh; Sara Najafi; Amirhossein Sahebkar; Zahra Sabouri; Majid Darroudi
Journal:  Biol Trace Elem Res       Date:  2021-06-10       Impact factor: 3.738
  7 in total

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