Autoradiographic studies of fracture healing using 99Tcm-Sn-polyphosphate.

Using 99Tcm-Sn-polyphosphate, macroautoradiographs were produced of 34 standardized, medullary-nailed, 1--10-week-old tibial fractures in the rat. The radioactivity was localized in the callus and epiphyseal growth plate. On microautoradiography the 99Tcm-Sn-polyphosphate was found diffusely scattered within the mineralizing part of the callus and the epiphyseal growth plate.