Literature DB >> 6489675

Enhancing effect of sodium taurocholate on N-methyl-N'-nitro-N-nitrosoguanidine-induced stomach tumorigenesis in rats.

O Kobori, J Watanabe, T Shimizu, M Shoji, Y Morioka.   

Abstract

Male Wistar rats that had received a low dose of N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) and sodium taurocholate showed a significantly higher incidence of hyperplastic and neoplastic lesions in the stomach mucosa than did the MNNG-treated controls. The result suggested an enhancing effect of taurocholate in stomach tumorigenesis.

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Year:  1984        PMID： 6489675

Source DB:  PubMed          Journal:  Gan        ISSN： 0016-450X


  7 in total

1.  Bile acids promote carcinogenesis in the remnant stomach of rats.

Authors:  A Kuwahara; T Saito; M Kobayashi
Journal:  J Cancer Res Clin Oncol       Date:  1989       Impact factor: 4.553

2.  Effects of sodium chloride and ethanol on stomach tumorigenesis in ACI rats treated with N-methyl-N'-nitro-N-nitrosoguanidine: a quantitative morphometric approach.

Authors:  H Watanabe; T Takahashi; T Okamoto; P O Ogundigie; A Ito
Journal:  Jpn J Cancer Res       Date:  1992-06

3.  Enhancement by thyroxine of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats.

Authors:  H Iishi; M Tatsuta; M Baba; R Yamamoto; H Taniguchi
Journal:  Br J Cancer       Date:  1993-09       Impact factor: 7.640

4.  Progesterone enhancement of stomach tumor development in SD rats treated with N-methyl-N'-nitro-N-nitrosoguanidine.

Authors:  Y Ando; H Watanabe; N Fujimoto; A Ito; T Toge
Journal:  Jpn J Cancer Res       Date:  1995-10

5.  The effects of sodium chloride, miso or ethanol on development of intestinal metaplasia after X-irradiation of the rat glandular stomach.

Authors:  H Watanabe; T Okamoto; T Takahashi; P O Ogundigie; A Ito
Journal:  Jpn J Cancer Res       Date:  1992-12

6.  Synergism between sodium chloride and sodium taurocholate and development of pepsinogen-altered pyloric glands: relevance to a medium-term bioassay system for gastric carcinogens and promoters in rats.

Authors:  M Tatematsu; M Mutai; K Inoue; K Ozaki; C Furihata; N Ito
Journal:  Jpn J Cancer Res       Date:  1989-11

7.  Elevated serum growth hormone accelerates gastric tumorigenesis in F344 rats after treatment with N-methyl-N-nitrosourea in their drinking water.

Authors:  H Watanabe; N Fujimoto; K Kawamoto; Y Ando; K Yamada; T Okamoto; G N Kanin; A Ito
Journal:  Jpn J Cancer Res       Date:  1995-07
  7 in total

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