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Literature DB >> 648935

Absence of K cells in human gut mucosa.

Abstract

Lymphocytes have been isolated from human rectal biopsies in numbers sufficient for microassay procedures. No antibody-dependent cell-mediated cytotoxic (ADCC) activity could be detected in normal or inflamed human gut mucosa, using two assay systems which detect predominantly K cell activity. The tissue localisation and circulation characteristics of K cells require definition before establishing their role as an efferent immunological mechanism.

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Mesh：

Year: 1978 PMID： 648935 PMCID： PMC1411922 DOI： 10.1136/gut.19.4.273

Source DB: PubMed Journal: Gut ISSN： 0017-5749 Impact factor: 23.059

10 in total

1. Characterization of mononuclear effector cells in human blood.

Authors: P Hersey; A Edwards; J Edwards
Journal: Clin Exp Immunol Date: 1976-01 Impact factor: 4.330

2. Effector cell activity in antibody mediated cell dependent immune lysis. II. Evidence for different populations of effector cells for different targets.

Authors: T Kovithavongs; G Rice; K L Thong; J B Dossetor
Journal: Cell Immunol Date: 1975-07 Impact factor: 4.868

3. Bacterial hemagglutination and hemolysis.

Authors: E NETER
Journal: Bacteriol Rev Date: 1956-09

4. Cytotoxic effector cell function in organized gut-associated lymphoid tissue (GALT).

Authors: D L Nelson; B M Bundy; R M Blaese; W Strober
Journal: Cell Immunol Date: 1976-03-01 Impact factor: 4.868

5. Immunological reactivity of the lung II. Cytotoxic effector function of pulmonary mononuclear cell subpopulations.

Authors: G W Hunninghake; A S Fauci
Journal: Cell Immunol Date: 1976-09 Impact factor: 4.868

6. Fatalities during remission of childhood leukemia.

Authors: J V Simone; E Holland; W Johnson
Journal: Blood Date: 1972-06 Impact factor: 22.113

7. Detection of antibodies which can cooperate with lymphocytes.

Authors: O Fakhri; J R Hobbs
Journal: Lancet Date: 1972-08-26 Impact factor: 79.321

8. Lysis of antibody-treated human erythrocytes by human leukocytes and macrophages in tissue culture.

Authors: G Holm
Journal: Int Arch Allergy Appl Immunol Date: 1972

9. The cytotoxic activity of lymphocytes from human lymph in vitro.

Authors: G Holm; C Franksson; A C Campbell; I C Maclennan
Journal: Clin Exp Immunol Date: 1974-07 Impact factor: 4.330

10. Cytotoxic lymphocytes in Hashimoto thyroiditis. An in vitro assay system using 51 Cr-labelled chicken red blood cells coated with thyroglobulin.

Authors: B A Calder; W J Penhale; E W Barnes; W J Irvine
Journal: Clin Exp Immunol Date: 1973-05 Impact factor: 4.330

10 in total

17 in total

1. Gut mucosal lymphocytes in inflammatory bowel disease: isolation and preliminary functional characterization.

Authors: C Fiocchi; J R Battisto; R G Farmer
Journal: Dig Dis Sci Date: 1979-09 Impact factor: 3.199

2. Isolation of spontaneous and interferon inducible natural killer like cells from human colonic mucosa: lysis of lymphoid and autologous epithelial target cells.

Authors: S Targan; L Britvan; R Kendal; S Vimadalal; A Soll
Journal: Clin Exp Immunol Date: 1983-10 Impact factor: 4.330

Absence of K cells in human gut mucosa.

1. Characterization of mononuclear effector cells in human blood.

2. Effector cell activity in antibody mediated cell dependent immune lysis. II. Evidence for different populations of effector cells for different targets.

3. Bacterial hemagglutination and hemolysis.

4. Cytotoxic effector cell function in organized gut-associated lymphoid tissue (GALT).

5. Immunological reactivity of the lung II. Cytotoxic effector function of pulmonary mononuclear cell subpopulations.

6. Fatalities during remission of childhood leukemia.

7. Detection of antibodies which can cooperate with lymphocytes.

8. Lysis of antibody-treated human erythrocytes by human leukocytes and macrophages in tissue culture.

9. The cytotoxic activity of lymphocytes from human lymph in vitro.

10. Cytotoxic lymphocytes in Hashimoto thyroiditis. An in vitro assay system using 51 Cr-labelled chicken red blood cells coated with thyroglobulin.

1. Gut mucosal lymphocytes in inflammatory bowel disease: isolation and preliminary functional characterization.

2. Isolation of spontaneous and interferon inducible natural killer like cells from human colonic mucosa: lysis of lymphoid and autologous epithelial target cells.

3. Depressed spontaneous cell-mediated cytotoxicity in Crohn's disease.

4. Lymphocyte subpopulations of intestinal mucosa in inflammatory bowel disease.

5. Immunological abnormalities involving the thymus in ulcerative colitis and therapeutic effects of thymectomy.

6. K-Cell activity in lamina proprial lymphocytes from the human colon.

7. Immune status in Crohn's disease. 4. In vitro antibody dependent cell mediated cytotoxicity in peripheral blood.

8. Preparation and purification of lymphocytes from the epithelium and lamina propria of murine small intestine.

9. Human colonic mononuclear cells: studies of cytotoxic function.

10. The early appearance of specific cytotoxic T cells in murine gut mucosa.