Literature DB >> 6488028

[3H]Kainic acid binding and choline acetyltransferase activity in Alzheimer's dementia.

B R Pearce, D M Bowen.   

Abstract

The binding of [3H]kainic acid to caudate nucleus membranes prepared from brains of examples of Alzheimer's dementia and controls has been determined. No changes were detected in either the affinity or the number of kainate binding sites in the Alzheimer samples compared to control, although there was a large decrease in choline acetyltransferase activity.

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Year:  1984        PMID: 6488028     DOI: 10.1016/0006-8993(84)90164-1

Source DB:  PubMed          Journal:  Brain Res        ISSN: 0006-8993            Impact factor:   3.252


  1 in total

1.  Imbalance of a serotonergic system in frontotemporal dementia: implication for pharmacotherapy.

Authors:  D M Bowen; A W Procter; D M A Mann; J S Snowden; M M Esiri; D Neary; P T Francis
Journal:  Psychopharmacology (Berl)       Date:  2007-11-18       Impact factor: 4.530

  1 in total

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