Literature DB >> 6488004

Release of pentobarbital-induced depression of metabolic rate during bilateral ischemia in the gerbil brain.

B B Mrsulja, Y Ueki, A Wheaton, J V Passonneau, W D Lust.   

Abstract

Treatment of gerbils with 40 mg/kg of pentobarbital (i.p.) reduced the metabolic rate in the hippocampus and cerebral cortex by approximately 60%. However, the depression of metabolic rate was lost within 40 s of ischemia and further, pentobarbital delayed but did not prevent the depletion of energy metabolites observed in the ischemic brain.

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Year:  1984        PMID: 6488004     DOI: 10.1016/0006-8993(84)91020-5

Source DB:  PubMed          Journal:  Brain Res        ISSN: 0006-8993            Impact factor:   3.252


  1 in total

1.  Low dose of barbiturates for prevention of hippocampal lesions after brief ischemic episodes.

Authors:  J Hallmayer; K A Hossmann; G Mies
Journal:  Acta Neuropathol       Date:  1985       Impact factor: 17.088

  1 in total

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