Literature DB >> 6486271

Case report of barbiturate-induced enhancement of methadone metabolism and withdrawal syndrome.

S J Liu, R I Wang.   

Abstract

A methadone maintenance patient with a decreased plasma methadone level, possibly due to phenobarbital-induced acceleration of methadone biotransformation, experienced opioid withdrawal symptoms. This finding suggests that when phenobarbital is used with methadone the plasma methadone level must be monitored.

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Year:  1984        PMID： 6486271     DOI： 10.1176/ajp.141.10.1287

Source DB:  PubMed          Journal:  Am J Psychiatry        ISSN： 0002-953X            Impact factor:   18.112


  9 in total

1.  Psychophysiological reactions in methadone maintenance patients do not correlate with methadone plasma levels.

Authors:  N Loimer; R Schmid; J Grünberger; R Jagsch; L Linzmayer; O Presslich
Journal:  Psychopharmacology (Berl)       Date:  1991       Impact factor: 4.530

Review 2.  Methadone maintenance in the treatment of opioid dependence. A current perspective.

Authors:  J E Zweben; J T Payte
Journal:  West J Med       Date:  1990-05

Review 3.  Interindividual variability of the clinical pharmacokinetics of methadone: implications for the treatment of opioid dependence.

Authors:  Chin B Eap; Thierry Buclin; Pierre Baumann
Journal:  Clin Pharmacokinet       Date:  2002       Impact factor: 6.447

4.  A single dose of methadone inhibits cytochrome P-4503A activity in healthy volunteers as assessed by the urinary cortisol ratio.

Authors:  D W Boulton; P Arnaud; C L DeVane
Journal:  Br J Clin Pharmacol       Date:  2001-04       Impact factor: 4.335

5.  Steady-state pharmacokinetics of methadone in opioid addicts.

Authors:  K Wolff; A W Hay; D Raistrick; R Calvert
Journal:  Eur J Clin Pharmacol       Date:  1993       Impact factor: 2.953

6.  Methadone N-demethylation in human liver microsomes: lack of stereoselectivity and involvement of CYP3A4.

Authors:  D J Foster; A A Somogyi; F Bochner
Journal:  Br J Clin Pharmacol       Date:  1999-04       Impact factor: 4.335

Review 7.  Interindividual variability of methadone response: impact of genetic polymorphism.

Authors:  Yongfang Li; Jean-Pierre Kantelip; Pauline Gerritsen-van Schieveen; Siamak Davani
Journal:  Mol Diagn Ther       Date:  2008       Impact factor: 4.074

Review 8.  Drug interactions of clinical significance with opioid analgesics.

Authors:  P M Maurer; R R Bartkowski
Journal:  Drug Saf       Date:  1993-01       Impact factor: 5.606

Review 9.  Antiepileptic drugs. A review of clinically significant drug interactions.

Authors:  P N Patsalos; J S Duncan
Journal:  Drug Saf       Date:  1993-09       Impact factor: 5.606
  9 in total

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