Oscillatory potentials, flash and pattern-reversal electroretinograms in amblyopia.

Oscillatory potentials (OP), flash and pattern-reversal electroretinograms (ERG) were recorded in 8 adult patients with amblyopia (visual acuity 0.3 or less) and 10 age-matched normal controls. No significant differences were observed in OPs between amblyopic and opposite eyes and normal controls. The pattern-reversal ERGs were significantly reduced in all amblyopic eyes. No significant side difference was found in the flash ERGs. The observed amplitude reduction in the pattern-reversal ERG might reflect dysfunction of the retinal ganglion cells, which have been supposed to be the main source of this type of ERG. No electrophysiological evidence could be demonstrated for a disturbed retinal function prior to the ganglion cell level.