Literature DB >> 6485187

Effect of gossypol on bull spermatozoa in vitro.

E Rovan, N R Kalla, J Frick, H Adam.   

Abstract

Gossypol acetic acid in a concentration of 1,000 microgram/ml solvent is able to immobilize 1 ml of native bull semen (sperm concentration: 8.5 X 10(8)/ml; motility rate: 87.4%) within 30 min. After GAA treatment the spermatozoa show severe morphological damage on the membrane system, on the acrosomal complex and on the tubular complex of the end piece. The working mechanism of GAA can be assumed to be inactivation of enzyme activities or in direct reactions with plasma membrane material.

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Year:  1984        PMID: 6485187     DOI: 10.1007/bf00255921

Source DB:  PubMed          Journal:  Urol Res        ISSN: 0300-5623


  11 in total

1.  [The agar-tube method for electron microscopical preparation of cell suspensions and small tissue fragments (author's transl)].

Authors:  E Rovan; P Simonsberger
Journal:  Mikroskopie       Date:  1974-06

2.  Gossypol, a powerful inhibitor of human spermatozoal metabolism.

Authors:  H Pösö; K Wichmann; J Jänne; T Luukkainen
Journal:  Lancet       Date:  1980-04-19       Impact factor: 79.321

3.  Scanning electron microscopic study of spermatozoa from gossypol-treated rats.

Authors:  S A Bozek; D R Jensen; J N Tone
Journal:  Cell Tissue Res       Date:  1981       Impact factor: 5.249

4.  Effects of Gossypol on the fertility of male rats, hamsters and rabbits.

Authors:  M C Chang; Z Gu; S K Saksena
Journal:  Contraception       Date:  1980-05       Impact factor: 3.375

5.  Effect of gossypol on the ultrastructure of rat spermatozoa.

Authors:  M J Nadakavukaren; R H Sorensen; J N Tone
Journal:  Cell Tissue Res       Date:  1979-12       Impact factor: 5.249

6.  In vitjro spermicidal activity of gossypol.

Authors:  D P Waller; L J Zaneveld; H H Fong
Journal:  Contraception       Date:  1980-08       Impact factor: 3.375

7.  Antifertility efficacy of gossypol acetic acid in male rats.

Authors:  G F Weinbauer; E Rovan; J Frick
Journal:  Andrologia       Date:  1982 May-Jun       Impact factor: 2.775

8.  Effect of gossypol on boar spermatozoa in vitro.

Authors:  W W Tso; C S Lee
Journal:  Arch Androl       Date:  1981-08

9.  Antifertility and endocrine activities of gossypol in rodents.

Authors:  D W Hahn; C Rusticus; A Probst; R Homm; A N Johnson
Journal:  Contraception       Date:  1981-07       Impact factor: 3.375

10.  Studies on the male antifertility agent--gossypol acetic acid. III. Effect of gossypol acetic acid on rat testis.

Authors:  N R Kalla; M Vasudev; G Arora
Journal:  Andrologia       Date:  1981 May-Jun       Impact factor: 2.775

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