Literature DB >> 6481451

Redistribution of acetylcholine receptors on developing rat myotubes.

L Ziskind-Conhaim, I Geffen, Z W Hall.   

Abstract

The mechanism of formation of acetylcholine receptor (AChR) clusters at developing mammalian endplates was investigated in vitro, using intercostal muscles from embryonic rats. The muscles were explanted in organ culture with the spinal cord attached, as described previously (Ziskind-Conhaim, L., and M. J. Dennis (1981) Dev. Biol. 85: 243-251). AChRs on the myofibers were labeled with [125I]-alpha-bungarotoxin shortly before clusters appeared and subsequently were cultured in unlabeled toxin for 1 day. Autoradiography of the cultured fibers demonstrated the presence of labeled clusters of AChRs indicating that the AChRs in the newly formed clusters arise from AChRs that had previously been uniformly distributed on the muscle surface.

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Year:  1984        PMID： 6481451      PMCID： PMC6564810     

Source DB:  PubMed          Journal:  J Neurosci        ISSN： 0270-6474            Impact factor:   6.167


  21 in total

1.  Cooperation between the products of different nuclei in hybrid myotubes produces localized acetylcholine receptor clusters.

Authors:  H Gordon; E Ralston; Z W Hall
Journal:  Proc Natl Acad Sci U S A       Date:  1992-07-15       Impact factor: 11.205

2.  Acetylcholinesterase mobility and stability at the neuromuscular junction of living mice.

Authors:  Isabel Martinez-Pena y Valenzuela; Mohammed Akaaboune
Journal:  Mol Biol Cell       Date:  2007-05-30       Impact factor: 4.138

3.  Acetylcholine receptor-inducing factor from chicken brain increases the level of mRNA encoding the receptor alpha subunit.

Authors:  D A Harris; D L Falls; R M Dill-Devor; G D Fischbach
Journal:  Proc Natl Acad Sci U S A       Date:  1988-03       Impact factor: 11.205

4.  Adherent primary cultures of mouse intercostal muscle fibers for isolated fiber studies.

Authors:  Patrick Robison; Erick O Hernández-Ochoa; Martin F Schneider
Journal:  J Biomed Biotechnol       Date:  2011-08-16

5.  Insertion and internalization of acetylcholine receptors at clustered and diffuse domains on cultured myotubes.

Authors:  S Bursztajn; S A Berman; J L McManaman; M L Watson
Journal:  J Cell Biol       Date:  1985-07       Impact factor: 10.539

6.  Distribution of alpha-dystroglycan during embryonic nerve-muscle synaptogenesis.

Authors:  M W Cohen; C Jacobson; E W Godfrey; K P Campbell; S Carbonetto
Journal:  J Cell Biol       Date:  1995-05       Impact factor: 10.539

7.  Acetylcholine receptor clustering is triggered by a change in the density of a nonreceptor molecule.

Authors:  J Stollberg; S E Fraser
Journal:  J Cell Biol       Date:  1990-11       Impact factor: 10.539

8.  Aggregating factor from Torpedo electric organ induces patches containing acetylcholine receptors, acetylcholinesterase, and butyrylcholinesterase on cultured myotubes.

Authors:  B G Wallace
Journal:  J Cell Biol       Date:  1986-03       Impact factor: 10.539

9.  300-kD subsynaptic protein copurifies with acetylcholine receptor-rich membranes and is concentrated at neuromuscular synapses.

Authors:  M L Woodruff; J Theriot; S J Burden
Journal:  J Cell Biol       Date:  1987-04       Impact factor: 10.539

10.  Regulation of agrin-induced acetylcholine receptor aggregation by Ca++ and phorbol ester.

Authors:  B G Wallace
Journal:  J Cell Biol       Date:  1988-07       Impact factor: 10.539
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