| Literature DB >> 6480217 |
Abstract
Syntheses by solution methods of tryptophyllins -4 and -5 (TPH-4 and TPH-5), tetra- and pentapeptides isolated from the skin extracts of the South American frog Phyllomedusa rhodei, are reported. The incorporation of the Pro2-Pro3 sequence into pentapeptides and the use of flash chromatography for purification of intermediates and target compounds are discussed. Preliminary biological results seem to indicate a growth-promoting activity for this peptide family.Entities:
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Year: 1984 PMID: 6480217 DOI: 10.1111/j.1399-3011.1984.tb00941.x
Source DB: PubMed Journal: Int J Pept Protein Res ISSN: 0367-8377