Literature DB >> 6479249

In vivo observation of lens protein diffusivity in normal and X-irradiated rabbit lenses.

I Nishio, J N Weiss, T Tanaka, J I Clark, F J Giblin, V N Reddy, G B Benedek.   

Abstract

Using the techniques of quasielastic light scattering spectroscopy we have studied in vivo the effect of X-irradiation on the diffusivity of lens proteins as a function of position in the lens and time after irradiation. The findings were compared with those for normal lenses in vivo. The experimentally observed correlation functions show marked changes in the protein diffusivity well before substantial biochemical changes take place.

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Year:  1984        PMID： 6479249     DOI： 10.1016/0014-4835(84)90115-5

Source DB:  PubMed          Journal:  Exp Eye Res        ISSN： 0014-4835            Impact factor:   3.467


  6 in total

Review 1.  The transparent lens and cornea in the mouse and zebra fish eye.

Authors:  Teri M S Greiling; John I Clark
Journal:  Semin Cell Dev Biol       Date:  2007-10-30       Impact factor: 7.727

2.  Aggregation of lens crystallins in an in vivo hyperbaric oxygen guinea pig model of nuclear cataract: dynamic light-scattering and HPLC analysis.

Authors:  M Francis Simpanya; Rafat R Ansari; Kwang I Suh; Victor R Leverenz; Frank J Giblin
Journal:  Invest Ophthalmol Vis Sci       Date:  2005-12       Impact factor: 4.799

3.  Phase separation in lens cytoplasm is genetically linked to cataract formation in the Philly mouse.

Authors:  J I Clark; D Carper
Journal:  Proc Natl Acad Sci U S A       Date:  1987-01       Impact factor: 11.205

4.  Automated, computerized, feature-based phenotype analysis of slit lamp images of the mouse lens.

Authors:  Jenny Yuen; Yi Li; Linda G Shapiro; John I Clark; Ernest Arnett; E Helene Sage; James F Brinkley
Journal:  Exp Eye Res       Date:  2007-12-07       Impact factor: 3.467

5.  Longitudinal Study of Age-Related Cataract Using Dynamic Light Scattering: Loss of α-Crystallin Leads to Nuclear Cataract Development.

Authors:  Manuel B Datiles; Rafat R Ansari; Junko Yoshida; Holly Brown; Andrea I Zambrano; Jing Tian; Susan Vitale; J Samuel Zigler; Frederick L Ferris; Sheila K West; Walter J Stark
Journal:  Ophthalmology       Date:  2015-11-03       Impact factor: 12.079

6.  Dynamic light scattering spectroscopy of the retina-a non-invasive quantitative technique to objectively document visual improvement following ocular stem cell treatment.

Authors:  Jeffrey N Weiss; Steven Levy
Journal:  Stem Cell Investig       Date:  2019-04-01
  6 in total

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