| Literature DB >> 647721 |
R A EdSilva, R L Verrier, B Lown.
Abstract
Administration of morphine sulphate to 16 anaesthetised dogs resulted in significant reduction in ventricular vulnerability to fibrillation. The repetitive extrasystole threshold was used as an index of vulnerability to ventricular fibrillation. In 14 dogs, atropine or vagotomy abolished this response. This suggests that central vagal activation by morphine sulphate may be protective against ventricular fibrillation.Entities:
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Year: 1978 PMID： 647721 DOI： 10.1093/cvr/12.3.167
Source DB: PubMed Journal: Cardiovasc Res ISSN： 0008-6363 Impact factor: 10.787