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Literature DB >> 6476412

Mosaicism of the ventricular layer as the developmental basis of neocortical columnar organization. A 3H-thymidine autoradiographic study in newborn mice.

Abstract

The ratio and local distribution of intensely and weakly labelled neurons as compared with unlabelled neurons were studied in newborn mice by means of autoradiography using 3H-thymidine injected at various embryonic ages. The distribution and migrational properties of intensely labelled neurons suggest that cells contributing to any given cortical layer are not generated simultaneously but in smaller units that correspond to cortical microcolumns. This implies a mosaicity in the genetic potential of the ventricular germinative layer.

Entities: Chemical Species

Mesh：

Substances：
Tritium
Thymidine

Year: 1984 PMID： 6476412 DOI： 10.1007/bf00319464

Source DB: PubMed Journal: Anat Embryol (Berl) ISSN： 0340-2061

27 in total

5. The location of nuclei of different labelling intensities in autoradiographs of the anterior forebrain of postnatial mice injected with [3H]thymidine on the eleventh and twelfth days post-conception.

Authors: I H Smart; M Smart
Journal: J Anat Date: 1977-04 Impact factor: 2.610

9. On the development of non-pyramidal neurons and axons outside the cortical plate: the early marginal zone as a pallial anlage.

Authors: M Rickmann; B M Chronwall; J R Wolff
Journal: Anat Embryol (Berl) Date: 1977-12-02

10. The structural organization of layer IV in the somatosensory region (SI) of mouse cerebral cortex. The description of a cortical field composed of discrete cytoarchitectonic units.

Authors: T A Woolsey; H Van der Loos
Journal: Brain Res Date: 1970-01-20 Impact factor: 3.252

2 in total

Review 1. Cell lineage and cell migration in the developing cerebral cortex.

Authors: C Walsh; C L Cepko
Journal: Experientia Date: 1990-09-15

2. Postnatal development of the human primary motor cortex: a quantitative cytoarchitectonic analysis.

Authors: K Amunts; V Istomin; A Schleicher; K Zilles
Journal: Anat Embryol (Berl) Date: 1995-12

2 in total

Mosaicism of the ventricular layer as the developmental basis of neocortical columnar organization. A 3H-thymidine autoradiographic study in newborn mice.

1. Autoradiographic study of development of the cerebral cortex in the rabbit.

2. Cell migrations to the isocortex in the rat.

3. Cell proliferation, migration and differentiation in the cerebral cortex of the golden hamster.

4. The migration of neuroblasts in the developing cerebral cortex.

5. The location of nuclei of different labelling intensities in autoradiographs of the anterior forebrain of postnatial mice injected with [3H]thymidine on the eleventh and twelfth days post-conception.

6. Proceedings: Numbers of neurons through full depth of neocortex.

7. Proliferation of different cell types in the brain.

8. Guidance of neurons migrating to the fetal monkey neocortex.

9. On the development of non-pyramidal neurons and axons outside the cortical plate: the early marginal zone as a pallial anlage.

10. The structural organization of layer IV in the somatosensory region (SI) of mouse cerebral cortex. The description of a cortical field composed of discrete cytoarchitectonic units.

Review 1. Cell lineage and cell migration in the developing cerebral cortex.

2. Postnatal development of the human primary motor cortex: a quantitative cytoarchitectonic analysis.