Literature DB >> 6475903

Elevated SGOT/SGPT ratio in alcoholic patients with acetaminophen hepatotoxicity.

D U Himmelstein, S J Woolhandler, R D Adler.   

Abstract

Two alcoholic patients with acetaminophen hepatotoxicity are described. Both patients had very high SGOT levels and SGOT/SGPT ratios. It is suggested that a high SGOT/SGPT ratio is not specific for alcoholic hepatitis. Extreme elevations of this ratio, especially in association with SGOT levels greater than five times normal, should suggest nonalcoholic causes of hepatocellular necrosis in alcoholic patients.

Entities:  

Mesh:

Substances:

Year:  1984        PMID: 6475903

Source DB:  PubMed          Journal:  Am J Gastroenterol        ISSN: 0002-9270            Impact factor:   10.864


  8 in total

1.  Acetaminophen liver injury.

Authors:  J B Simon
Journal:  Can Fam Physician       Date:  1985-11       Impact factor: 3.275

2.  Liver function tests.

Authors:  R Cramb; C M Florkowski
Journal:  BMJ       Date:  1990-09-15

Review 3.  The de ritis ratio: the test of time.

Authors:  Mona Botros; Kenneth A Sikaris
Journal:  Clin Biochem Rev       Date:  2013-11

Review 4.  Effects of non-narcotic analgesics on the liver.

Authors:  L F Prescott
Journal:  Drugs       Date:  1986       Impact factor: 9.546

5.  Treatment of alcoholic liver disease.

Authors:  Thomas H Frazier; Abigail M Stocker; Nicole A Kershner; Luis S Marsano; Craig J McClain
Journal:  Therap Adv Gastroenterol       Date:  2011-01       Impact factor: 4.409

Review 6.  [Drug interactions in pain therapy].

Authors:  K M J Syhr; B G Oertel; G Geisslinger
Journal:  Schmerz       Date:  2015-12       Impact factor: 1.107

Review 7.  Paracetamol, alcohol and the liver.

Authors:  L F Prescott
Journal:  Br J Clin Pharmacol       Date:  2000-04       Impact factor: 4.335

8.  Should a lower treatment line be used when treating paracetamol poisoning in patients with chronic alcoholism?: a case against.

Authors:  Paul I Dargan; Alison L Jones
Journal:  Drug Saf       Date:  2002       Impact factor: 5.606

  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.