| Literature DB >> 6474160 |
I J East, A M Keenan, S M Larson, J Dean.
Abstract
The zona pellucida is an extracellular glycocalyx, made of three sulfated glycoproteins, that surrounds mammalian oocytes. Parenterally administered monoclonal antibodies specific for ZP-2, the most abundant zona protein, localize in the zona pellucida. When labeled with iodine-125, these monoclonal antibodies demonstrate a remarkably high target-to-nontarget tissue ratio and provide clear external radioimaging of ovarian tissue.Entities:
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Year: 1984 PMID： 6474160 DOI： 10.1126/science.6474160
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728