| Literature DB >> 6474156 |
J T Clark, E R Smith, J M Davidson.
Abstract
Yohimbine hydrochloride, an alpha 2-adrenoceptor antagonist, increased sexual motivation in male rats as evidenced by increased mounting performance in mating tests conducted after genital anesthetization, increased percentage of male rats ejaculating in their first heterosexual encounter, and induction of copulatory behavior in sexually inactive male rats. These observations lead to the suggestion that alpha-adrenoceptors are important modulators of sexual arousal in intact male rats. These results indicate that pharmacological treatment of sexual (libido) dysfunction may be useful.Entities:
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Year: 1984 PMID： 6474156 DOI： 10.1126/science.6474156
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728