| Literature DB >> 6471112 |
Abstract
Two cases are reported describing the use of intravenous naloxone in surgical patients with prolonged hypotension unresponsive to conventional intensive care, including dopamine, intravenous fluids, diuretics, and steroids.The findings were in agreement with those of previous reports suggesting that endorphins may contribute to the hypotension of sepsis and that naloxone's antagonistic effect on endorphin may have therapeutic value in the treatment of septic shock.Entities:
Mesh：
Substances：
Year: 1984 PMID： 6471112 PMCID： PMC2561640
Source DB: PubMed Journal: J Natl Med Assoc ISSN： 0027-9684 Impact factor: 1.798