Literature DB >> 6471063

Cardiotonic agents. 1. 4,5-Dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3 (2H)-pyridazinones: novel positive inotropic agents for the treatment of congestive heart failure.

J A Bristol, I Sircar, W H Moos, D B Evans, R E Weishaar.   

Abstract

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Year:  1984        PMID： 6471063     DOI： 10.1021/jm00375a001

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  12 in total

1.  Actions of the phosphodiesterase inhibitor zardaverine on guinea-pig ventricular muscle.

Authors:  M Galvan; C Schudt
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1990-08       Impact factor: 3.000

2.  Toward the identification of the cardiac cGMP inhibited-phosphodiesterase catalytic site.

Authors:  P Fossa; R Boggia; L Mosti
Journal:  J Comput Aided Mol Des       Date:  1998-07       Impact factor: 3.686

3.  The presence of five cyclic nucleotide phosphodiesterase isoenzyme activities in bovine tracheal smooth muscle and the functional effects of selective inhibitors.

Authors:  M Shahid; R G van Amsterdam; J de Boer; R E ten Berge; C D Nicholson; J Zaagsma
Journal:  Br J Pharmacol       Date:  1991-10       Impact factor: 8.739

4.  In vivo pharmacological studies with SK&F 94836, a potent inotrope/vasodilator with a sustained duration of action.

Authors:  R W Gristwood; M B Comer; R J Eden; E M Taylor; J A Turner; M Wallduck; D A Owen
Journal:  Br J Pharmacol       Date:  1988-04       Impact factor: 8.739

5.  A comparative study of the cardiovascular and biochemical actions of the imidazo [4,5b] pyridine sulmazole and an imidazo [4,5c] pyridine analogue, BW A746C.

Authors:  G Allan; D Cambridge; M J Follenfant; D Stone; M V Whiting
Journal:  Br J Pharmacol       Date:  1988-02       Impact factor: 8.739

6.  The insulin- and glucagon-stimulated 'dense-vesicle' high-affinity cyclic AMP phosphodiesterase from rat liver. Purification, characterization and inhibitor sensitivity.

Authors:  N J Pyne; M E Cooper; M D Houslay
Journal:  Biochem J       Date:  1987-02-15       Impact factor: 3.857

7.  The positive inotropic response to milrinone in isolated human and guinea pig myocardium.

Authors:  L Brown; M Näbauer; E Erdmann
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1986-10       Impact factor: 3.000

Review 8.  Milrinone. A preliminary review of its pharmacological properties and therapeutic use.

Authors:  R A Young; A Ward
Journal:  Drugs       Date:  1988-08       Impact factor: 9.546

9.  Additive positive inotropic effects of milrinone, ouabain and calcium in diseased human ventricular myocardium.

Authors:  L Brown; M Näbauer; E Erdmann
Journal:  Klin Wochenschr       Date:  1986-08-01

10.  The matching of electrostatic extrema: a useful method in drug design? A study of phosphodiesterase III inhibitors.

Authors:  R P Apaya; B Lucchese; S L Price; J G Vinter
Journal:  J Comput Aided Mol Des       Date:  1995-02       Impact factor: 3.686
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