Literature DB >> 6468612

Metabolic implications in the elevation of serum activity of intestinal alkaline phosphatase in chronic renal failure.

J Stĕpán, T Havránek, E Jelínková, M Straková, J Skrha, V Pacovský.   

Abstract

The activity of intestinal isoenzyme of serum alkaline phosphatase was evaluated in 21 non-dialyzed patients with advanced renal failure and in 52 patients on regular hemodialysis. In patients without hepatopathy, a significant inverse correlation was found between the enzyme activity and serum calcium levels. Hepatopathy was the most significant variable influencing the enzyme activity in patients on dialysis. Secondary hyperparathyroidism and a decreased rate in enzyme elimination should be assessed for the above-normal activities of intestinal ALP in serum in chronic renal failure.

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Year:  1984        PMID： 6468612     DOI： 10.1007/bf01952015

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  10 in total

1.  A modified inactivation-inhibition method for determining the serum activity of alkaline phosphatase isoenzymes.

Authors:  J Stĕpán; V Volek; J Kolár
Journal:  Clin Chim Acta       Date:  1976-05-17       Impact factor: 3.786

2.  Intestinal alkaline phosphatase in serum of patients on maintenance haemodialysis.

Authors:  A W Walker
Journal:  Clin Chim Acta       Date:  1974-09-30       Impact factor: 3.786

3.  Letter: Increased intestinal alkaline phosphatase in serum of patients on maintenance haemodialysis.

Authors:  M E De Broe; V Bosteels; R J Wieme
Journal:  Lancet       Date:  1974-04-20       Impact factor: 79.321

4.  Rapid colorimetric determination of calcium in biologic fluids with methylthymol blue.

Authors:  E M Gindler; J D King
Journal:  Am J Clin Pathol       Date:  1972-10       Impact factor: 2.493

5.  A new and convenient colorimetric determination of inorganic orthophosphate and its application to the assay of inorganic pyrophosphatase.

Authors:  J K Heinonen; R J Lahti
Journal:  Anal Biochem       Date:  1981-05-15       Impact factor: 3.365

6.  Binding of calcium ions to the isolated asialo-glycoprotein receptor. Implications for receptor function in suspended hepatocytes.

Authors:  R Blomhoff; H Tolleshaug; T Berg
Journal:  J Biol Chem       Date:  1982-07-10       Impact factor: 5.157

7.  Letter: Serum-alkaline-phosphatase during maintenance haemodialysis.

Authors:  J Stepán; T Pilarova
Journal:  Lancet       Date:  1975-05-24       Impact factor: 79.321

8.  Correlation of serum L-phenylalanine-sensitive alkaline phosphatase, derived from intestine, with the ABO blood group of cirrhotics.

Authors:  L L Stolbach; M J Krant; N I Inglis; W H Fishman
Journal:  Gastroenterology       Date:  1967-05       Impact factor: 22.682

9.  Serum inhibitors of desialylated glycoprotein binding to hepatocyte membranes.

Authors:  J S Marshall; S Williams
Journal:  Biochim Biophys Acta       Date:  1978-09-21

10.  Indentification of an intestinal sodium and calcium-dependent phosphatase stimulated by parathyroid hormone.

Authors:  S J Birge; H R Gilbert
Journal:  J Clin Invest       Date:  1974-09       Impact factor: 14.808
  10 in total

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