Literature DB >> 6468605

(3H) spiroperidol binding decreases in brains of rats infected with Venezuelan equine encephalomyelitis virus.

E Bonilla, M Salazar, J Estevez, H Hernández, P Rangel.   

Abstract

After i.p. inoculation with the Guajira strain of Venezuelan equine encephalomyelitis virus a significant decrease in the density of (3H) spiroperidol binding sites in the striatum, midbrain and frontal cortex was observed. No changes in the affinity of the receptors could be demonstrated. This finding is compatible with neuronal degeneration caused by the viral infection.

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Year:  1984        PMID： 6468605     DOI： 10.1007/bf01952000

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  11 in total

1.  Venezuelan equine encephalomyelitis virus infection: effect on monoamine metabolism of mouse brain.

Authors:  E Bonilla; S Ryder; H Hernandez
Journal:  J Neurochem       Date:  1975-10       Impact factor: 5.372

2.  Spiperone: a ligand of choice for neuroleptic receptors. 1. Kinetics and characteristics of in vitro binding.

Authors:  J E Leysen; W Gommeren; P M Laduron
Journal:  Biochem Pharmacol       Date:  1978-02-01       Impact factor: 5.858

3.  Spiperone: a ligand of choice for neuroleptic receptors. 3. Subcellular distribution of neuroleptic drugs and their receptors in various rat brain areas.

Authors:  P M Laduron; P F Janssen; J E Leysen
Journal:  Biochem Pharmacol       Date:  1978-02-01       Impact factor: 5.858

4.  Serotonergic component of neuroleptic receptors.

Authors:  J E Leysen; C J Niemegeers; J P Tollenaere; P M Laduron
Journal:  Nature       Date:  1978-03-09       Impact factor: 49.962

5.  Binding of 3H-neuroleptics and 3H-apomorphine in schizophrenic brains.

Authors:  T Lee; P Seeman; W W Tourtellotte; I J Farley; O Hornykeiwicz
Journal:  Nature       Date:  1978-08-31       Impact factor: 49.962

6.  Tyrosine hydroxylase activity in Venezuelan equine encephalomyelitis virus infection.

Authors:  S Levine; E Bonilla; S Ryder; M Salazar; P Rangel
Journal:  Neurochem Res       Date:  1981-06       Impact factor: 3.996

7.  Effect of Venezuelan equine encephalomyelitis virus infection on brain choline acetyltransferase and acetylcholinesterase activities.

Authors:  E Bonilla; H Hernández; M Salazar; P Rangel
Journal:  Brain Res       Date:  1982-12-16       Impact factor: 3.252

8.  GABA metabolism in Venezuelan equine encephalomyelitis virus infection.

Authors:  E Bonilla; E Ryder; S Ryder
Journal:  Neurochem Res       Date:  1980-02       Impact factor: 3.996

9.  Regional studies of catecholamines in the rat brain. I. The disposition of [3H]norepinephrine, [3H]dopamine and [3H]dopa in various regions of the brain.

Authors:  J Glowinski; L L Iversen
Journal:  J Neurochem       Date:  1966-08       Impact factor: 5.372

10.  Central nervous system alterations as sequelae of Venezuelan equine encephalitis virus infection in the rat.

Authors:  J García-Tamayo; G Carreño; J Esparza
Journal:  J Pathol       Date:  1979-06       Impact factor: 7.996
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  1 in total

1.  Serotonin turnover rate in raphe and cortex of mice infected with Venezuelan equine encephalomyelitis virus.

Authors:  L Lima; R Walder; F Obregón; B Drujan
Journal:  J Neurosci Res       Date:  1987       Impact factor: 4.164
  1 in total

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