| Literature DB >> 6468530 |
Abstract
Following intratesticular injection of [3H]thymidine, spermatozoa were isolated from the caput and cauda epididymis of CD-1 mice. Quantitation of the amount of radiolabelled DNA in whole spermatozoa, sperm heads (nuclei) and sperm midpiece-tails (mitochondria) at time intervals 3-36 days postinjection demonstrated mitochondrial DNA (mtDNA) is synthesized during meiosis and early spermiogenesis. mtDNA synthesis terminates in mid-spermiogenesis suggesting that the mitochondrial genome in spermatozoa has a half-life of at least 15 days.Entities:
Mesh：
Substances：
Year: 1984 PMID： 6468530 DOI： 10.1016/0014-4827(84)90688-8
Source DB: PubMed Journal: Exp Cell Res ISSN： 0014-4827 Impact factor: 3.905