Literature DB >> 646828

Lymphopenia in systemic lupus erythematosus. Clinical, diagnostic, and prognostic significance.

S J Rivero, E Díaz-Jouanen, D Alarcón-Segovia.   

Abstract

One hundred fifty-eight patients with active, untreated systemic lupus erythematosus (SLE) were studied from the time of diagnosis. Lymphopenia was present in 75%, and another 18% of those patients developed lymphopenia subsequent to disease reactivation. Lymphopenia of less than 1500 cells/microliter occurred more frequently than any of the preliminary criteria for the classification of SLE, and it was the most prevalent initial laboratory abnormality. Lymphocyte counts were significantly lower in lupus than in the other connective tissue diseases except mixed connective tissue disease and polymyositis.

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Year:  1978        PMID: 646828     DOI: 10.1002/art.1780210302

Source DB:  PubMed          Journal:  Arthritis Rheum        ISSN: 0004-3591


  32 in total

1.  Effect of mycophenolate mofetil on the white blood cell count and the frequency of infection in systemic lupus erythematosus.

Authors:  Ananta Subedi; Laurence S Magder; Michelle Petri
Journal:  Rheumatol Int       Date:  2015-04-03       Impact factor: 2.631

2.  Prevalence and pathogenicity of autoantibodies in patients with idiopathic CD4 lymphopenia.

Authors:  Ainhoa Perez-Diez; Chun-Shu Wong; Xiangdong Liu; Harry Mystakelis; Jian Song; Yong Lu; Virginia Sheikh; Jeffrey S Bourgeois; Andrea Lisco; Elizabeth Laidlaw; Cornelia Cudrici; Chengsong Zhu; Quan-Zhen Li; Alexandra F Freeman; Peter R Williamson; Megan Anderson; Gregg Roby; John S Tsang; Richard Siegel; Irini Sereti
Journal:  J Clin Invest       Date:  2020-10-01       Impact factor: 14.808

Review 3.  Lessons learned from bone marrow failure in systemic lupus erythematosus: Case reports and review of the literature.

Authors:  Erik Anderson; Bhakti Shah; Anne Davidson; Richard Furie
Journal:  Semin Arthritis Rheum       Date:  2017-12-08       Impact factor: 5.532

4.  Quantitative and functional profiles of CD4+ lymphocyte subsets in systemic lupus erythematosus patients with lymphopenia.

Authors:  D Gómez-Martín; M Díaz-Zamudio; G Vanoye; J C Crispín; J Alcocer-Varela
Journal:  Clin Exp Immunol       Date:  2011-01-14       Impact factor: 4.330

5.  IL-6 blocks a discrete early step in lymphopoiesis.

Authors:  Kazuhiko Maeda; Yoshihiro Baba; Yoshinori Nagai; Kozo Miyazaki; Alexander Malykhin; Koji Nakamura; Paul W Kincade; Nobuo Sakaguchi; K Mark Coggeshall
Journal:  Blood       Date:  2005-04-14       Impact factor: 22.113

Review 6.  Lymphocytotoxic antibodies in SLE: a review of the literature.

Authors:  C Osman; A J Swaak
Journal:  Clin Rheumatol       Date:  1994-03       Impact factor: 2.980

7.  Serum levels of soluble forms of T cell activation antigens CD27 and CD25 in systemic lupus erythematosus in relation with lymphocytes count and disease course.

Authors:  A J Swaak; R Q Hintzen; V Huysen; H G van den Brink; J T Smeenk
Journal:  Clin Rheumatol       Date:  1995-05       Impact factor: 2.980

8.  Risk factors of Pneumocystis jeroveci pneumonia in patients with systemic lupus erythematosus.

Authors:  Ratchaya Lertnawapan; Kitti Totemchokchyakarn; Kanokrat Nantiruj; Suchela Janwityanujit
Journal:  Rheumatol Int       Date:  2008-09-25       Impact factor: 2.631

9.  A new specific assay for the detection of DNA immune complexes: its relevance in SLE.

Authors:  P Klemp; O L Meyers; E H Harley
Journal:  Ann Rheum Dis       Date:  1983-06       Impact factor: 19.103

10.  Respiratory disease in systemic lupus erythematosus: correlation with results of laboratory tests and histological appearance of muscle biopsy specimens.

Authors:  S A Evans; N D Hopkinson; W J Kinnear; L Watson; R J Powell; I D Johnston
Journal:  Thorax       Date:  1992-11       Impact factor: 9.139

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