Literature DB >> 6467219

Cancer and other causes of death among embalmers.

J Walrath, J F Fraumeni.   

Abstract

To evaluate the potential carcinogenic effects of formaldehyde, we examined the proportionate mortality experience of embalmers licensed to practice in California. Mortality was significantly elevated for total cancer, arteriosclerotic heart disease, and suicide, whereas significant deficits were noted in mortality from diseases of the respiratory and genitourinary systems. Deaths from cancers of the brain, colon, and prostate and leukemia were significantly higher than expected. No increased mortality was seen for cancers of the respiratory tract, including the nasal passages, where an effect might be expected based on animal studies. A parallel mortality survey of embalmers from New York State showed similar findings, with excesses of brain tumors, leukemia, colon cancer, arteriosclerotic heart disease, and cirrhosis. Further investigation is needed to determine whether any of these outcomes is related to formaldehyde exposure.

Entities:  

Mesh:

Year:  1984        PMID: 6467219

Source DB:  PubMed          Journal:  Cancer Res        ISSN: 0008-5472            Impact factor:   12.701


  19 in total

1.  Identifying an indoor air exposure limit for formaldehyde considering both irritation and cancer hazards.

Authors:  Robert Golden
Journal:  Crit Rev Toxicol       Date:  2011-06-02       Impact factor: 5.635

2.  Is exposure to formaldehyde in air causally associated with leukemia?--A hypothesis-based weight-of-evidence analysis.

Authors:  Lorenz R Rhomberg; Lisa A Bailey; Julie E Goodman; Ali K Hamade; David Mayfield
Journal:  Crit Rev Toxicol       Date:  2011-06-02       Impact factor: 5.635

3.  A case-control study of occupational risk factors for laryngeal cancer.

Authors:  P Wortley; T L Vaughan; S Davis; M S Morgan; D B Thomas
Journal:  Br J Ind Med       Date:  1992-12

4.  Formaldehyde and the risk of squamous cell carcinoma of the sinonasal cavities.

Authors:  J H Olsen; S Asnaes
Journal:  Br J Ind Med       Date:  1986-11

5.  Occupational exposure to formaldehyde, hematotoxicity, and leukemia-specific chromosome changes in cultured myeloid progenitor cells.

Authors:  Luoping Zhang; Xiaojiang Tang; Nathaniel Rothman; Roel Vermeulen; Zhiying Ji; Min Shen; Chuangyi Qiu; Weihong Guo; Songwang Liu; Boris Reiss; Laura Beane Freeman; Yichen Ge; Alan E Hubbard; Ming Hua; Aaron Blair; Noe Galvan; Xiaolin Ruan; Blanche P Alter; Kerry X Xin; Senhua Li; Lee E Moore; Sungkyoon Kim; Yuxuan Xie; Richard B Hayes; Mariko Azuma; Michael Hauptmann; Jun Xiong; Patricia Stewart; Laiyu Li; Stephen M Rappaport; Hanlin Huang; Joseph F Fraumeni; Martyn T Smith; Qing Lan
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2010-01       Impact factor: 4.254

Review 6.  Cancer effects of formaldehyde: a proposal for an indoor air guideline value.

Authors:  Gunnar Damgård Nielsen; Peder Wolkoff
Journal:  Arch Toxicol       Date:  2010-05-14       Impact factor: 5.153

7.  Mortality from lymphohematopoietic malignancies and brain cancer among embalmers exposed to formaldehyde.

Authors:  Michael Hauptmann; Patricia A Stewart; Jay H Lubin; Laura E Beane Freeman; Richard W Hornung; Robert F Herrick; Robert N Hoover; Joseph F Fraumeni; Aaron Blair; Richard B Hayes
Journal:  J Natl Cancer Inst       Date:  2009-12-16       Impact factor: 13.506

Review 8.  Formaldehyde and cancer: a critical review.

Authors:  J K McLaughlin
Journal:  Int Arch Occup Environ Health       Date:  1994       Impact factor: 3.015

9.  Mortality from lymphohematopoietic malignancies among workers in formaldehyde industries: the National Cancer Institute Cohort.

Authors:  Laura E Beane Freeman; Aaron Blair; Jay H Lubin; Patricia A Stewart; Richard B Hayes; Robert N Hoover; Michael Hauptmann
Journal:  J Natl Cancer Inst       Date:  2009-05-12       Impact factor: 13.506

Review 10.  Formaldehyde and leukemia: epidemiology, potential mechanisms, and implications for risk assessment.

Authors:  Luoping Zhang; Laura E Beane Freeman; Jun Nakamura; Stephen S Hecht; John J Vandenberg; Martyn T Smith; Babasaheb R Sonawane
Journal:  Environ Mol Mutagen       Date:  2010-04       Impact factor: 3.216

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