| Literature DB >> 6466983 |
Y Ohta, M Ariyoshi, K Koketsu.
Abstract
The mechanism of an inhibitory effect of histamine on the sensitivity of frog skeletal muscle endplate was analyzed by studying the dose-response relation between the quantity of ACh applied iontophoretically and the ACh-induced postsynaptic current (ACh current), and also the interaction between histamine and erabutoxin-b (ETX-b). The results obtained show that histamine, like curare, decreased the sensitivity of ACh-receptor in a competitive manner.Entities:
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Year: 1984 PMID： 6466983 DOI： 10.1016/0006-8993(84)90389-5
Source DB: PubMed Journal: Brain Res ISSN： 0006-8993 Impact factor: 3.252