Literature DB >> 646682

Acetazolamide in the treatment of pyruvate dysmetabolism syndromes.

O B Evans, A W Kilroy, G M Fenichel.   

Abstract

Two children with periodic weakness beginning in infancy were demonstrated to have abnormalities in pyruvate metabolism by the production of lactic acidosis following a glucose load. Daily oral doses of acetazolamide reduced the frequency of attacks and reversed the abnormal response to glucose loading. The mechanism of action of acetazolamide in these patients is not clear.

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Year:  1978        PMID: 646682     DOI: 10.1001/archneur.1978.00500290048008

Source DB:  PubMed          Journal:  Arch Neurol        ISSN: 0003-9942


  3 in total

Review 1.  Mitochondrial myopathies. Clinical, morphological and biochemical aspects.

Authors:  R C Sengers; A M Stadhouders; J M Trijbels
Journal:  Eur J Pediatr       Date:  1984-02       Impact factor: 3.183

2.  Oxygen uptake and carbon dioxide elimination after acetazolamide in the critically ill.

Authors:  P Berthelsen; I Gøthgen; B Husum; E Jacobsen
Journal:  Intensive Care Med       Date:  1985       Impact factor: 17.440

3.  X-linked Leigh's syndrome.

Authors:  P J Benke; J C Parker; M L Lubs; J Benkendorf; A E Feuer
Journal:  Hum Genet       Date:  1982       Impact factor: 4.132

  3 in total

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