Literature DB >> 6466137

[Myocardial changes after spinal cord injuries in humans and experimental animals].

V G Sharov, K A Galakhin.   

Abstract

The hearts of 15 persons dying within one day after the trauma of the spinal cord as well as the hearts of 50 laboratory animals (rats and dogs) were examined histologically, histochemically and by electron microscopy. Cardiomyocytes demonstrated in both conditions (autopsy and experimental) many early contractual alterations. Electron microscopy of experimental material with the use of colloid lanthanum showed, already 15 minutes after the trauma of the spinal cord, the indirect signs of overloading the contractile cells with calcium this being the main cause of acute heart failure immediately after the spinal cord trauma.

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Year:  1984        PMID: 6466137

Source DB:  PubMed          Journal:  Arkh Patol        ISSN: 0004-1955


  5 in total

1.  Structural neuroplasticity following T5 spinal cord transection: increased cardiac sympathetic innervation density and SPN arborization.

Authors:  Heidi L Lujan; Gurunanthan Palani; Stephen E DiCarlo
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2010-07-28       Impact factor: 3.619

2.  Direct comparison of cervical and high thoracic spinal cord injury reveals distinct autonomic and cardiovascular consequences.

Authors:  Heidi L Lujan; Stephen E DiCarlo
Journal:  J Appl Physiol (1985)       Date:  2020-01-30

3.  Paraplegia increased cardiac NGF content, sympathetic tonus, and the susceptibility to ischemia-induced ventricular tachycardia in conscious rats.

Authors:  Heidi L Lujan; Ying Chen; Stephen E Dicarlo
Journal:  Am J Physiol Heart Circ Physiol       Date:  2009-03-13       Impact factor: 4.733

4.  Fundamental hemodynamic mechanisms mediating the response to myocardial ischemia in conscious paraplegic mice: cardiac output versus peripheral resistance.

Authors:  Heidi L Lujan; Stephen E DiCarlo
Journal:  Physiol Rep       Date:  2017-03

5.  Angiotensin-(1-7) Receptor Mas Deficiency Does Not Exacerbate Cardiac Atrophy Following High-Level Spinal Cord Injury in Mice.

Authors:  Anne Järve; Fatimunnisa Qadri; Mihail Todiras; Shirley Schmolke; Natalia Alenina; Michael Bader
Journal:  Front Physiol       Date:  2020-03-12       Impact factor: 4.566

  5 in total

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