Literature DB >> 6463915

A dose response study of oxitropium bromide in chronic bronchitis.

E T Peel, G Anderson.   

Abstract

In a dose response study 12 patients with chronic bronchitis and airflow obstruction received inhaled placebo and incremental doses of oxitropium bromide. Significant improvements in peak expiratory flow rate, forced expiratory volume in one second, and forced vital capacity were recorded at all times up to 10 hours after all doses of oxitropium bromide. Oxitropium bromide is an effective bronchodilator in chronic bronchitis with an optimal dose of 400-600 micrograms.

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Year:  1984        PMID： 6463915      PMCID： PMC459829          DOI： 10.1136/thx.39.6.453

Source DB:  PubMed          Journal:  Thorax        ISSN： 0040-6376            Impact factor:   9.139


  2 in total

1.  Peak expiratory flow in normal subjects.

Authors:  I Gregg; A J Nunn
Journal:  Br Med J       Date:  1973-08-04

2.  Definition and classification of chronic bronchitis for clinical and epidemiological purposes. A report to the Medical Research Council by their Committee on the Aetiology of Chronic Bronchitis.

Authors: 
Journal:  Lancet       Date:  1965-04-10       Impact factor: 79.321
  2 in total
  7 in total

1.  Comparison of the bronchodilating effect of oxitropium bromide and fenoterol in asthmatic children.

Authors:  H P Van Bever; K N Desager; J H Pauwels; P A Vermeire
Journal:  Eur J Pediatr       Date:  1994-08       Impact factor: 3.183

2.  Acute effect of pretreatment with single conventional dose of salmeterol on dose-response curve to oxitropium bromide in chronic obstructive pulmonary disease.

Authors:  M Cazzola; F Di Perna; S Centanni; C Califano; C F Donner; M D'Amato; G D'Amato
Journal:  Thorax       Date:  1999-12       Impact factor: 9.139

3.  Oxygen desaturation and breathlessness during corridor walking in chronic obstructive pulmonary disease: effect of oxitropium bromide.

Authors:  D P Spence; J G Hay; J Carter; M G Pearson; P M Calverley
Journal:  Thorax       Date:  1993-11       Impact factor: 9.139

4.  The effect of anticholinergic bronchodilator therapy on cough during upper respiratory tract infections.

Authors:  R Lowry; A Wood; T Higenbottam
Journal:  Br J Clin Pharmacol       Date:  1994-02       Impact factor: 4.335

5.  Effect of long term treatment with oxitropium bromide on airway secretion in chronic bronchitis and diffuse panbronchiolitis.

Authors:  J Tamaoki; A Chiyotani; E Tagaya; N Sakai; K Konno
Journal:  Thorax       Date:  1994-06       Impact factor: 9.139

6.  Dose-response study of oxitropium bromide inhaled as a nebulised solution.

Authors:  I Stappaerts; L Van Schil; J Van der Veken
Journal:  Eur J Clin Pharmacol       Date:  1994       Impact factor: 2.953

7.  Comparative dose-response study of three anticholinergic agents and fenoterol using a metered dose inhaler in patients with chronic obstructive pulmonary disease.

Authors:  A Ikeda; K Nishimura; H Koyama; T Izumi
Journal:  Thorax       Date:  1995-01       Impact factor: 9.139
  7 in total

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