Literature DB >> 6463648

Nuclear localization and DNA binding properties of a protein expressed by human c-myc oncogene.

H Persson, P Leder.   

Abstract

Antisera to the human cellular myc oncogene product were used to identify a human c-myc specific protein with a molecular weight of 65,000. Subcellular fractionation showed that the human c-myc protein is predominantly found in the cell nucleus. The p65Kc-myc protein binds to double- and single-stranded DNA as measured by a DNA affinity chromatography assay.

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Year:  1984        PMID： 6463648     DOI： 10.1126/science.6463648

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  86 in total

Review 1.  Reactive oxygen intermediates involved in cellular regulation.

Authors:  B Meier
Journal:  Protoplasma       Date:  2001       Impact factor: 3.356

2.  The leucine zipper of c-Myc is required for full inhibition of erythroleukemia differentiation.

Authors:  M J Smith; D C Charron-Prochownik; E V Prochownik
Journal:  Mol Cell Biol       Date:  1990-10       Impact factor: 4.272

3.  Translocation of a store of maternal cytoplasmic c-myc protein into nuclei during early development.

Authors:  M Gusse; J Ghysdael; G Evan; T Soussi; M Méchali
Journal:  Mol Cell Biol       Date:  1989-12       Impact factor: 4.272

4.  Two N-myc polypeptides with distinct amino termini encoded by the second and third exons of the gene.

Authors:  T P Mäkelä; K Saksela; K Alitalo
Journal:  Mol Cell Biol       Date:  1989-04       Impact factor: 4.272

5.  E1A-dependent trans-activation of the human MYC promoter is mediated by the E2F factor.

Authors:  S W Hiebert; M Lipp; J R Nevins
Journal:  Proc Natl Acad Sci U S A       Date:  1989-05       Impact factor: 11.205

6.  Insertional activation of N-myc by endogenous Moloney-like murine retrovirus sequences in macrophage cell lines derived from myeloma cell line-macrophage hybrids.

Authors:  M Setoguchi; Y Higuchi; S Yoshida; N Nasu; Y Miyazaki; S Akizuki; S Yamamoto
Journal:  Mol Cell Biol       Date:  1989-10       Impact factor: 4.272

7.  Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis.

Authors:  Bora Gurel; Tsuyoshi Iwata; Cheryl M Koh; Robert B Jenkins; Fusheng Lan; Chi Van Dang; Jessica L Hicks; James Morgan; Toby C Cornish; Siobhan Sutcliffe; William B Isaacs; Jun Luo; Angelo M De Marzo
Journal:  Mod Pathol       Date:  2008-06-20       Impact factor: 7.842

8.  Nuclear colocalization of cellular and viral myc proteins with HSP70 in myc-overexpressing cells.

Authors:  P J Koskinen; L Sistonen; G Evan; R Morimoto; K Alitalo
Journal:  J Virol       Date:  1991-02       Impact factor: 5.103

9.  Human proto-oncogene N-myc encodes nuclear proteins that bind DNA.

Authors:  G Ramsay; L Stanton; M Schwab; J M Bishop
Journal:  Mol Cell Biol       Date:  1986-12       Impact factor: 4.272

10.  Rapid induction of polyadenylated H1 histone mRNAs in mouse erythroleukemia cells is regulated by c-myc.

Authors:  G H Cheng; A I Skoultchi
Journal:  Mol Cell Biol       Date:  1989-06       Impact factor: 4.272
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