Literature DB >> 6462991

Does hyperthyroidism predispose to thioridazine-induced hyperpyrexia and cardiac arrhythmias?

M B Murphy, M X FitzGerald.   

Abstract

Treatment with thioridazine resulted in hyperpyrexia and ventricular tachycardia in a young woman who was later shown to have thyrotoxicosis. The reasons why hyperthyroidism may enhance thioridazine toxicity are reviewed.

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Year:  1984        PMID： 6462991      PMCID： PMC2417892          DOI： 10.1136/pgmj.60.704.445

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN： 0032-5473            Impact factor:   2.401


  10 in total

1.  HYPOTHERMIA FOLLOWING CHLORPROMAZINE THERAPY IN MYXOEDEMATOUS PATIENTS.

Authors:  I H JONES; T W MEADE
Journal:  Gerontol Clin (Basel)       Date:  1964

2.  Thioridazine-induced hyperpyrexia--a case report.

Authors:  A I Jacknowitz
Journal:  Am J Hosp Pharm       Date:  1979-05

3.  Recurrent major ventricular arrhythmias associated with thioridazine therapy.

Authors:  R J Rosenquist; W W Brauer; J N Mork
Journal:  Minn Med       Date:  1971-11

4.  Death associated with ventricular arrhythmia and thioridazine hydrochloride.

Authors:  T D Giles; R K Modlin
Journal:  JAMA       Date:  1968-07-08       Impact factor: 56.272

5.  Temperature changes induced by chlorpromazine and N-methyl chlorpromazine in the rat.

Authors:  W E Kirkpatrick; P Lomax
Journal:  Neuropharmacology       Date:  1971-01       Impact factor: 5.250

6.  Thyroxine-induced changes in characteristics and activities of beta-adrenergic receptors and adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate systems in the heart may be related to reputed catecholamine supersensitivity in hyperthyroidism.

Authors:  J Tse; R W Wrenn; J F Kuo
Journal:  Endocrinology       Date:  1980-07       Impact factor: 4.736

7.  The effect of thioridazine hydrochloride and chlorpromazine on the electrocardiogram.

Authors:  J R Huston; G E Bell
Journal:  JAMA       Date:  1966-10-03       Impact factor: 56.272

8.  Malignant hyperthermia. An allergic reaction to thioridazine therapy.

Authors:  M L Haberman
Journal:  Arch Intern Med       Date:  1978-05

9.  Effects of thioridazine (Mellaril) on ventricular electrophysiologic properties.

Authors:  M S Yoon; J Han; G H Dersham; S A Jones
Journal:  Am J Cardiol       Date:  1979-06       Impact factor: 2.778

10.  Death attributed to ventricular arrhythmia induced by thioridazine in combination with a single Contac C capsule.

Authors:  G Chouinard; A M Ghadirian; B D Jones
Journal:  Can Med Assoc J       Date:  1978-10-07       Impact factor: 8.262
  10 in total

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