Present state of the coacervate-in-coacervate theory; origin and evolution of cell structure.

In agreement with the views of Oparin, Fox, Dose etc., the theory assumes that coacervation of protein-like polyaminoacids began with their accumulation along the coasts of the Archaic water basins. Unlike the above authors, however, the present author views the original coacervates as a suitable "culture medium" from which the first polynucleotides originated and their partial replication started. Their base sequence was not fortuitous, but determined by the proteinoids on the basis of their mutual affinity. The polyfunctional enzymic activity of the proteinoids catalyzed their replication as well as other activities. Around the replicating DNA molecules secondary coacervates (coacervates in coacervates) accumulated which developed gradually to the first prokaryotic cells. Their most probable evolution to the first eukaryotic organisms is discussed on the basis of the modified Studitsky's synbacteriogenesis theory.