Conjunctival melanosis and melanoma.

A clinicopathologic study of 41 cases of primary acquired melanosis has provided information concerning the rate of progression to melanoma and has provided histologic parameters useful in predicting which lesions are likely to progress to malignant melanoma. A clinicopathologic study of 131 conjunctival melanomas has provided information concerning the clinical and histologic parameters associated with a fatal outcome. Highlights of these two studies are presented together with implications for diagnosis and therapy.