Literature DB >> 6461859

Characterization of a porcine genomic clone encoding a major histocompatibility antigen: expression in mouse L cells.

D S Singer, R D Camerini-Otero, M L Satz, B Osborne, D Sachs, S Rudikoff.   

Abstract

A porcine genomic clone encoding a major histocompatibility, (MHC) antigen was isolated by direct screening of a swine genomic library with a heterologous human MHC cDNA probe. Mouse L cells transformed with DNA from the clone stably express swine MHC antigen. Pig alloantisera specifically lyse transformant but not control cell lines in a complement-mediated cytotoxicity assay. Direct immunoprecipitation of radiolabeled cellular protein from transformed lines by pig alloantiserum results in the coprecipitation of swine MHC heavy chain and mouse beta 2-microglobulin, demonstrating the association of heterologous subunits of MHC antigens.

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Year:  1982        PMID： 6461859      PMCID： PMC345981          DOI： 10.1073/pnas.79.5.1403

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  32 in total

1.  Rapid isolation of antigens from cells with a staphylococcal protein A-antibody adsorbent: parameters of the interaction of antibody-antigen complexes with protein A.

Authors:  S W Kessler
Journal:  J Immunol       Date:  1975-12       Impact factor: 5.422

2.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

3.  Transplantation in miniature swine. I. Fixation of the major histocompatibility complex.

Authors:  D H Sachs; G Leight; J Cone; S Schwarz; L Stuart; S Rosenberg
Journal:  Transplantation       Date:  1976-12       Impact factor: 4.939

4.  Analysis of repeating DNA sequences by reassociation.

Authors:  R J Britten; D E Graham; B R Neufeld
Journal:  Methods Enzymol       Date:  1974       Impact factor: 1.600

5.  The immunologic response to xenografts. Recognition of mouse H-2 histocompatibility antigens by the rat.

Authors:  D H Sachs; H J Winn; P S Russell
Journal:  J Immunol       Date:  1971-08       Impact factor: 5.422

6.  Association of a beta2-microglobulin-like subunit with H-2 and TL alloantigens on murine thymocytes.

Authors:  E S Vitetta; J W Uhr; E A Boyse
Journal:  J Immunol       Date:  1975-01       Impact factor: 5.422

7.  The H-2 major histocompatibility complex and the I immune response region: genetic variation, function, and organization.

Authors:  D C Shreffler; C S David
Journal:  Adv Immunol       Date:  1975       Impact factor: 3.543

8.  Transplantation in miniature swine. II. In vitro parameters of histocompatibility in MSLA homozygous minipigs.

Authors:  G S Leight; D H Sachs; S A Rosenberg
Journal:  Transplantation       Date:  1977-03       Impact factor: 4.939

9.  Nucleotide sequence of the rightward operator of phage lambda.

Authors:  T Maniatis; A Jeffrey; D G Kleid
Journal:  Proc Natl Acad Sci U S A       Date:  1975-03       Impact factor: 11.205

10.  Molecular similarities between the Qa-2 alloantigen and other gene products of the 17th chromosome of the mouse.

Authors:  J Michaelson; L Flaherty; E Vitetta; M D Poulik
Journal:  J Exp Med       Date:  1977-04-01       Impact factor: 14.307
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  37 in total

1.  Impairment of MHC class I transcription in a mutant bovine B cell line.

Authors:  J S Harms; G A Splitter
Journal:  Immunogenetics       Date:  1992       Impact factor: 2.846

2.  Frequent segmental sequence exchanges and rapid gene duplication characterize the MHC class I genes in lemurs.

Authors:  Yasuhiro Go; Yoko Satta; Yoshi Kawamoto; Gilbert Rakotoarisoa; Albert Randrianjafy; Naoki Koyama; Hirohisa Hirai
Journal:  Immunogenetics       Date:  2003-10-03       Impact factor: 2.846

3.  Mapping of the SLA complex of miniature swine: mapping of the SLA gene complex by pulsed field gel electrophoresis.

Authors:  Y Xu; M F Rothschild; C M Warner
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

4.  ATG deserts define a novel core promoter subclass.

Authors:  Maxwell P Lee; Kevin Howcroft; Aparna Kotekar; Howard H Yang; Kenneth H Buetow; Dinah S Singer
Journal:  Genome Res       Date:  2005-08-18       Impact factor: 9.043

5.  Cloning and sequencing of the porcine complement factor B.

Authors:  L J Peelman; A R Van de Weghe; W R Coppieters; A J Van Zeveren; Y H Bouquet
Journal:  Immunogenetics       Date:  1991       Impact factor: 2.846

6.  Mapping and genetic organization of the TNF genes in the swine Mhc.

Authors:  P Chardon; M Nunes; F Dezeure; D Andrès-Cara; M Vaiman
Journal:  Immunogenetics       Date:  1991       Impact factor: 2.846

7.  Production of monoclonal antibodies reactive with polymorphic and monomorphic determinants of SLA class I gene products.

Authors:  D Ivanoska; D C Sun; J K Lunney
Journal:  Immunogenetics       Date:  1991       Impact factor: 2.846

8.  Regulation of MHC class I expression by Foxp3 and its effect on regulatory T cell function.

Authors:  Jie Mu; Xuguang Tai; Shankar S Iyer; Jocelyn D Weissman; Alfred Singer; Dinah S Singer
Journal:  J Immunol       Date:  2014-02-12       Impact factor: 5.422

9.  Identification of human genomic clones coding the major histocompatibility antigens HLA-a2 and HLA-B7 by DNA-mediated gene transfer.

Authors:  J A Barbosa; M E Kamarck; P A Biro; S M Weissman; F H Ruddle
Journal:  Proc Natl Acad Sci U S A       Date:  1982-10       Impact factor: 11.205

10.  High-level expression of a cloned HLA heavy chain gene introduced into mouse cells on a bovine papillomavirus vector.

Authors:  D DiMaio; V Corbin; E Sibley; T Maniatis
Journal:  Mol Cell Biol       Date:  1984-02       Impact factor: 4.272
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